Sentences with phrase «hypercholesterolemia causes»

The genetic condition familial hypercholesterolemia causes blood - cholesterol levels three to seven times higher than normal in humans.

Using this approach, they demonstrate that the pathological features of inherited hypercholesterolemia caused by PCSK9 mutations can be reproduced in a Petri dish.

Not exact matches

That was for mipomersen, a medicine used to treat familial hypercholesterolemia, a hereditary condition that causes massive increases in LDL cholesterol.

An example comes from a patient with familial hypercholesterolemia — a disease that causes high blood levels of «bad» LDL (low - density lipoprotein) cholesterol because a cellular defect prevents the liver from absorbing LDL.

Inherited metabolic disorders, like familial hypercholesterolemia, alpha -1-antitrypsin deficiency, and glycogen storage diseases, involve defective genes that cause metabolic enzyme deficiencies and liver dysfunction.

Additionally, inherited metabolic disorders, like familial hypercholesterolemia, alpha -1-antitrypsin deficiency, and glycogen storage diseases, involve defective genes that cause metabolic enzyme deficiencies and liver dysfunction.

They showed that mutations in this receptor cause Familial Hypercholesterolemia, a disorder that leads to premature heart attacks.

They showed that mutations in this receptor cause Familial Hypercholesterolemia, a disorder that leads to premature heart attacks in one out of every 500 people in most populations.

Mipomersen (Kynamro) reduces low - density lipoprotein (LDL) cholesterol by silencing a gene that produces apolipoprotein B - 100, a building block of LDL; the drug can treat familial hypercholesterolemia, an inherited disease that may cause heart attacks at an early age.

A study from an international research team finds that familial hypercholesterolemia — a genetic condition that causes greatly elevated levels of LDL cholesterol throughout life — accounts for less than 2 percent of severely elevated LDL in the general population but also increases the risk of coronary artery disease significantly more than does elevated LDL alone.

The investigators also looked at a subgroup of patients with familial hypercholesterolemia, a genetic disorder that causes extremely high cholesterol that increases the risk of early heart disease.

Well, hypercholesterolemia is caused by copper deficiency.

As I've just argued that cardiovascular disease causes high LDL, it shouldn't be a surprise that copper deficiency also causes hypercholesterolemia: