Sentences with phrase «hypercholesterolemia in»

Promising studies have concluded that onions can be useful to reduce hypercholesterolemia in liver inflammation.

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That was for mipomersen, a medicine used to treat familial hypercholesterolemia, a hereditary condition that causes massive increases in LDL cholesterol.

Due to its fatty acid and high dietary fiber content, chia seeds are considered in holistic medicine to be beneficial in reducing cardiovascular risk factors including diabetes, hypercholesterolemia, hypertension and inflammation.

Palm Oil - Derived Natural Vitamin E a-Tocotrienol in Brain Health and Disease: Scientific literature evaluating the therapeutic potential of tocotrienols (type of vitamin E found in abundance in palm fruit oil) for neurodegenerative disorders of the central nervous system, cancer treatment, and hypercholesterolemia.

Statins are HMGR inhibitors with inhibition constant values in the nanomolar range that effectively lower serum cholesterol levels and are widely prescribed in the treatment of hypercholesterolemia.

«They were not developed for cancer, they were manufactured for people with hypercholesterolemia [chronic condition where patients have very high level of cholesterol in their blood], but it will be interesting for us to test them with cancer patients and see if there is improvement.»

Regulation of lipoprotein receptors can be exploited pharmacologically in the therapy of hypercholesterolemia and atherosclerosis is man.

Reported today in Disease Models & Mechanisms, Karim Si - Tayeb and colleagues in the research group of Bertrand Cariou from l'Institut du Thorax, Nantes used an innovative approach to develop unique patient cell - based models of PCSK9 - driven hypercholesterolemia.

Using this approach, they demonstrate that the pathological features of inherited hypercholesterolemia caused by PCSK9 mutations can be reproduced in a Petri dish.

Hypercholesterolemia (literally: high blood cholesterol) is the presence of high levels of cholesterol in the blood.

Researchers evaluated the effectiveness and safety of statin treatment in 214 children with familial hypercholesterolemia (FH).

A similar mutation, detected by S1 nuclease mapping of LDL receptor messenger RNA, occurred in a patient with familial hypercholesterolemia whose receptor also fails to be transported to the cell surface.

The role of the exogenous pathway in hypercholesterolemia.

They showed that mutations in this receptor cause Familial Hypercholesterolemia, a disorder that leads to premature heart attacks.

«These results suggest a significant polygenic contribution in individuals presenting with EOCAD [early onset coronary artery disease], which could be more prevalent than familial hypercholesterolemia,» the study states.

His research has focused on the progression and development of family medicine practice, particularly in the areas of smoking cessation, non-familial hypercholesterolemia and anxiety.

Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolemia;

They showed that mutations in this receptor cause Familial Hypercholesterolemia, a disorder that leads to premature heart attacks in one out of every 500 people in most populations.

Hypercholesterolemia - prone mice that were engrafted with bone marrow obtained from homozygous or heterozygous Tet2 knockout mice had larger atherosclerotic lesions in the aortic root and aorta than did mice that had received control bone marrow.

Their discovery of the LDL receptor as the major molecule regulating cholesterol metabolism and its genetic disruption in the human disease familial hypercholesterolemia have been recognized by their receipt of numerous awards, including the Nobel Prize in Physiology or Medicine (1985), the Albert D. Lasker Award in Basic Medical Research (1985), and the U.S. National Medal of Science (1988).

The genetic condition familial hypercholesterolemia causes blood - cholesterol levels three to seven times higher than normal in humans.

A study from an international research team finds that familial hypercholesterolemia — a genetic condition that causes greatly elevated levels of LDL cholesterol throughout life — accounts for less than 2 percent of severely elevated LDL in the general population but also increases the risk of coronary artery disease significantly more than does elevated LDL alone.

on hypercholesterolemia and lipid peroxidation in cholesterol - fed rats.

My cousin is professor in paediatrics and does research in familial hypercholesterolemia and has invented a pharmaceutical therapy, similar to PCSK 9 therapy.

The list of natural interventions for hypercholesterolemia mentioned in this article is not comprehensive; therefore, it is recommended to consult a health - care provider trained in natural medicine for proper dosing and to determine which interventions are appropriate.

[9] One study showed that consuming 2 g of plant sterols reduces the concentration of LDL - C in individuals with hypercholesterolemia by more than 10 % after 12 months.

In conclusion, hypercholesterolemia is complex and can be prevented and treated with lifestyle changes, such as increasing exercise and changing the diet.

[14] Psyllium is the most effective soluble fiber in treating hypercholesterolemia.

In the illustrations that accompany this Harvard study it says that the study was «adjusted for age; race; body - mass index; level of physical activity; status with regard to smoking, whether a physical examination was performed for screening purposes, current multivitamin use, and current aspirin use; status with regard to a family history of diabetes mellitus, myocardial infarction, or cancer; status with regard to a history of diabetes mellitus, hypertension, or hypercholesterolemia; intake of total energy, alcohol, RED OR PROCESSED MEAT, fruits, and vegetables; and, for women, menopausal status and hormone use.»

A diet high in polyunsaturated fats decreased CRP, IL - 6, sVCAM - 1, and E-selectin compared with the typical American diet among patients with hypercholesterolemia (32, 33).

[5]- Moundras, C., Remesy, C., Levrat, M., Demigne, C., Methionine Deficiency in Rats Fed Soy Protein Induces Hypercholesterolemia and Potentiates Lipoprotein Susceptibility to Peroxidation.

It was soon found to be effective in the prevention and treatment of angina pectoris, heart failure, diabetes, hypercholesterolemia and obesity.

Keep in mind that people with very high cholesterol levels on a ketogenic / low - carb diet may want to avoid eating too many eggs and other foods high in cholesterol (especially those with genetic disorders - ApoE4 gene and hypercholesterolemia).

-- Wei, Z. H., Wang, H., Chen, X. Y., et al (2009) Time - and dose - dependent effect of psyllium on serum lipids in mild - to - moderate hypercholesterolemia: a meta - analysis of controlled clinical trials.

A study concluded that taking psyllium twice daily, along with diet therapy, reduces LDL - cholesterol concentrations in men and women with primary hypercholesterolemia.

1) A genetic Condition called Familial Hypercholesterolemia which affects 1 in 500 people, where a person's liver expresses much less LDL receptors and is therefore unable to clear «used» cholesterol in LDL particles from the blood

He's already eating WFPB and may have familial hypercholesterolemia and in his case, drugs may be needed to reduce his risk.

Endothelial dysfunction is often seen in patients with coronary artery disease, diabetes mellitus, hypertension, and hypercholesterolemia.

Chahal N, McCrindle B, Manlhiot C et al. aA 4 - week randomized clinical trial of flaxseed supplementation in children with hypercholesterolemia.

The wealth of antioxidants in asparagus has the potential to treat oxidative stress, along with other disorders such as hyperlipidemia and hypercholesterolemia.

In an 8 - week intervention study in 34 men with type 2 diabetes and hypercholesterolemia consuming either 10.2 g / d of psyllium or cellulose, daily and postlunch postprandial glucose concentration were 11.0 and 19.2 percent lower, respectively, in the psyllium group (Anderson et al., 1999In an 8 - week intervention study in 34 men with type 2 diabetes and hypercholesterolemia consuming either 10.2 g / d of psyllium or cellulose, daily and postlunch postprandial glucose concentration were 11.0 and 19.2 percent lower, respectively, in the psyllium group (Anderson et al., 1999in 34 men with type 2 diabetes and hypercholesterolemia consuming either 10.2 g / d of psyllium or cellulose, daily and postlunch postprandial glucose concentration were 11.0 and 19.2 percent lower, respectively, in the psyllium group (Anderson et al., 1999in the psyllium group (Anderson et al., 1999).

Compari - son of psyllium hydrophilic mucilloid and cellulose as adjuncts to a prudent diet in the treatment of mild to moderate hypercholesterolemia.

Cholesterol - lowering effects of psyllium - enriched cereal as an adjunct to a prudent diet in the treatment of mild to moderate hypercholesterolemia.

Long - term effects of consuming foods containing psyllium seed husk on serum lipids in subjects with hypercholesterolemia.

A meta - analysis was conducted to determine the effect of consump - tion of psyllium - enriched cereal products on blood lipid concentrations in 404 adults with mild to moderate hypercholesterolemia consuming a low fat diet (Olson et al., 1997).

Effects of psyllium on glucose and serum lipid responses in men with type 2 diabetes and hypercholesterolemia.

Effects of guar gum in male subjects with hypercholesterolemia.

Similarly, Bell and coworkers (1990) tested the cholesterol - lowering effects of viscous fiber (psyllium or pectin) cereals as part of a diet in 58 men with mild to moderate hypercholesterolemia.

Hypercholesterolemia: a disease where the animal has too much cholesterol in the blood system.