Hyperglycemic is a word used to describe a condition when the level of sugar (glucose) in your blood is too high.
Full definition
This study builds on previous research by Dr. Li's laboratory that showed, for the first time, significant accumulation of succinate in the bone marrow and serum
of hyperglycemic mice.
Selective inhibition of 11ß - hydroxysteroid dehydrogenase type 1 improves hepatic insulin sensitivity in
hyperglycemic mice strains.
Because prior studies have shown that
hyperglycemic patients also exhibit elevated nasal glucose levels, it is likely that the sweet taste receptor function we demonstrate here may also contribute to the predisposition of diabetic patients to airway infections.»
In a chronic sleep deprivation experiment, young mice were sensitized to insulin and had improved control of their blood sugar, whereas aged animals
became hyperglycemic and failed to maintain appropriate plasma insulin concentrations.
Their protective effects were attributed, in part, to the avoidance of postprandial
hyperglycemic peaks (4, 5) because recurrent postprandial hyperglycemia results in overproduction of reactive free radical molecules and greater release of inflammatory cytokines (4, 6).
A study recently published in Clinical, Cosmetic, and Investigative Dermatology concluded that
hyperglycemic carbohydrates, dairy, and saturated fats are the three major food classes found to promote acne.
In the study, «Succinate and its G - protein - coupled receptor stimulate osteoclastogenesis,» the researchers took samples of bone marrow
from hyperglycemic male mice and healthy mice.
These results confirmed the sensitivity to estrogen of pancreatic alpha cells, which then secrete
less hyperglycemic glucagon, but more GLP1.
Paternal stress epigenetically downregulates miR - 466b - 3p expression, leading to increased PEPCK expression and hepatic gluconeogenesis in
hyperglycemic F1 mice.
Hyperglycemic clamp - derived disposition index is negatively associated with metabolic syndrome severity in obese subjects.
«
Hyperglycemic crises in adult patients with diabetes: a consensus statement from the American Diabetes Association».
i believe is the glycemic index in lentils, for example (which by the way lentils have one of the lowest glyc indexes), that helps in avoiding those
nasty hyperglycemic peaks
It
prevents hyperglycemic toxicity to neurons, pancreatic cells, the arterial walls and the generation of excessive levels of reactive oxygen species.
The problem is that blood sugar levels are still high (and the body isn't consuming that sugar), meaning that it has an extremely high risk of
developing hyperglycemic shock.
Victor objects to rice because of its high glycemic index, an issue which we've addressed in the book and on this blog in the safe starches debate and my post on how to
avoid hyperglycemic toxicity.
al Hader, A. A., Hasan, Z. A., and Aqel, M.
B. Hyperglycemic and insulin release inhibitory effects of Rosmarinus officinalis.
Hyperglycemic Hyperosmolar Nonketotic (HHNK) Syndrome: An uncommon complication of undiagnosed or unregulated diabetes, HHNK occurs when your cat's blood sugar rises so high that urine is produced at a higher rate than the cat can drink water.
As J Stanton commented, it would have been good to note that we recommend consuming «safe starches» as parts of meals, not as isolated snacks, and to discuss how meal design mitigates risk of
hyperglycemic toxicity:
Furthermore, the transgenic HSPCs were found to preferentially home to the pancreata of
hyperglycemic mice.
In my reply to Jimmy Moore's safe starches symposium (see Jimmy Moore's seminar on «safe starches»: My reply, Oct 12), I didn't quite have time to fully address the issue
of hyperglycemic toxicity.
In a study published in Nature Communications, the investigators report that
hyperglycemic mice (or mice with type 2 diabetes) have a 24-fold higher accumulation of succinate, an intermediate metabolite, in the metabolic pathways of their bone marrow stromal cells.
«In our study,
the hyperglycemic mice had increased bone resorption [the breakdown and absorption of old bone], which outpaced the formation of new bone.
Adoptive transfer of these cells resulted in reversion of
the hyperglycemic state in NOD mice, with reduced T cell infiltrates in the pancreas and increased circulating FoxP3 + regulatory T cells.
But please note that you do not need to be labeled «diabetic», «hypoglycemic», or «
hyperglycemic» in order to actually have problems with blood sugar metabolism.
To start out the day especially with fructose or even with a lot of starch, it just sets you up for
that hyperglycemic thing.
In
a hyperglycemic state, the affinity of aldose reductase for glucose rises, causing much sorbitol to accumulate.
It is like being born a sun - starved hypothyroid with messed up circadian rhythms who can't form muscle and is
hyperglycemic and dyslipidemic.
«Well how come obese people have obese children, despite the fetus being
an a hyperglycemic environment?»