Sentences with phrase «hyperglycemic mice»

«In our study, the hyperglycemic mice had increased bone resorption [the breakdown and absorption of old bone], which outpaced the formation of new bone.

In a study published in Nature Communications, the investigators report that hyperglycemic mice (or mice with type 2 diabetes) have a 24-fold higher accumulation of succinate, an intermediate metabolite, in the metabolic pathways of their bone marrow stromal cells.

Not exact matches

In the study, «Succinate and its G - protein - coupled receptor stimulate osteoclastogenesis,» the researchers took samples of bone marrow from hyperglycemic male mice and healthy mice.

Paternal stress epigenetically downregulates miR - 466b - 3p expression, leading to increased PEPCK expression and hepatic gluconeogenesis in hyperglycemic F1 mice.

In a chronic sleep deprivation experiment, young mice were sensitized to insulin and had improved control of their blood sugar, whereas aged animals became hyperglycemic and failed to maintain appropriate plasma insulin concentrations.

Adoptive transfer of these cells resulted in reversion of the hyperglycemic state in NOD mice, with reduced T cell infiltrates in the pancreas and increased circulating FoxP3 + regulatory T cells.

At 8 months of age, both DIO and DR groups had increased hyperglycemic response during a glucose tolerance test, which was normalized in 16 - month - old mice.

The healthy mice developed low - grade intestinal inflammation and a metabolic disorder that caused them to eat more, becoming obese, hyperglycemic, and resistant to insulin.