Sentences with word «hyperproliferation»

In this manuscript, we focused the role of miR - 142, one of the miRNAs upregulated in human BCSCs, and found that miR - 142 targets APC, up - regulates the Wnt signaling, and induced the expression of miR - 150 that has an ability to induce hyperproliferation of mammary tissues.

Helicobacter pylori induces hyperproliferation in a three - dimensional culture system in conjunction with up - regulation of ß - catenin target genes.

In human gastric tissue, however, gastric epithelial cell proliferation is significantly higher but apoptotic indices are lower among persons colonized with cag + compared to cag - strains or uninfected persons leading us to postulate that reduced rates of cell loss, when accompanied by hyperproliferation, may heighten retention of mutagenized cells, which could predispose towards cancer.

... Traditionally, broadband UVB phototherapy has been used to treat psoriasis, which is an inflammatory skin disease, characterized by keratinocyte hyperproliferation with 1 - 2 percent prevalence in the general population.

Excessive activation of lymphocytes (a form of white blood cells) are thought to be responsible for the short epidermal cell cycle that results in hyperproliferation of skin tissues.

The findings are particularly relevant for certain B cell pathologies, including lymphoma subtypes, where there is an increased demand for energy to support the hyperproliferation of cells in a microenvironment that may be limited in nutrients.»

Using a CRISPR - dCas9 epigenetic editing tool, the researchers methylated different genes in healthy breast cells and found that those changes were sufficient to cause the cells to undergo «hyperproliferation» — abnormally rapid cell division which is an early stage of tumour initiation.

DNA hypermethylation in prostate cancer is a consequence of aberrant epithelial differentiation and hyperproliferation.

Xiao C, Ogle SA, Schumacher MA, Orr - Asman MA, Miller ML, Lertkowit N. Loss of parietal cell expression of Sonic hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells.