Xiao C, Ogle SA, Schumacher MA, Orr - Asman MA, Miller ML, Lertkowit N. Loss of parietal cell expression of Sonic hedgehog induces hypergastrinemia and
hyperproliferation of surface mucous cells.
Excessive activation of lymphocytes (a form of white blood cells) are thought to be responsible for the short epidermal cell cycle that results in
hyperproliferation of skin tissues.
In this manuscript, we focused the role of miR - 142, one of the miRNAs upregulated in human BCSCs, and found that miR - 142 targets APC, up - regulates the Wnt signaling, and induced the expression of miR - 150 that has an ability to induce
hyperproliferation of mammary tissues.
Myeloproliferative neoplasms (MPNs) are a group of related clonal hemopoietic stem cell disorders associated with
hyperproliferation of myeloid cells.
Not exact matches
Using a CRISPR - dCas9 epigenetic editing tool, the researchers methylated different genes in healthy breast cells and found that those changes were sufficient to cause the cells to undergo «
hyperproliferation» — abnormally rapid cell division which is an early stage
of tumour initiation.
DNA hypermethylation in prostate cancer is a consequence
of aberrant epithelial differentiation and
hyperproliferation.
Helicobacter pylori induces
hyperproliferation in a three - dimensional culture system in conjunction with up - regulation
of ß - catenin target genes.
In human gastric tissue, however, gastric epithelial cell proliferation is significantly higher but apoptotic indices are lower among persons colonized with cag + compared to cag - strains or uninfected persons leading us to postulate that reduced rates
of cell loss, when accompanied by
hyperproliferation, may heighten retention
of mutagenized cells, which could predispose towards cancer.