Clinical signs include hematuria (blood in the urine), dysuria (painful urination), pollakiuria (frequent daytime urination), and sometimes lameness caused by
hypertrophic osteopathy (bone disease).
It is not only the earliest occurrence of fully - developed
hypertrophic pulmonary
osteopathy on an adult skeleton to date, but also clearly establishes the presence of tuberculosis in Europe 7,000 years ago.»
These may include: hip dysplasia, elbow dysplasia, osteochondrosis dessicans (OCD), craniomandibular
osteopathy (CMO),
hypertrophic osteodystrophy (HOD), eosinophilic panosteitis, Wobbler Syndrome, alantoaxial subluxation, Legg - Calve - Perthes» Disease, medial patellar luxation, eye diseases, subaortic stenosis, pulmonary stenosis, ventricular septal defect, patent ductus arteriosis, Tetralogy of Fallot, persistent right aortic arch, dilated cardiomyopathy, hemophilia, Von Willebrand's disease, epilepsy, hydrocephalus, intervertebral disk disease, mange, hypothyroidism, Cushing's Disease, pituitary dwarfism and autoimmune skin disorders.