Sentences with word «hypervariable»

The most common strategy to assess microbiota is sequencing specific hypervariable regions of 16S rRNA gene using 2nd generation platforms (such as MiSeq or Ion Torrent PGM).

All the samples were sequenced for the three hypervariable segments of the mitochondrial DNA (mtDNA) control region to assess the genetic composition of modern Mongolia.â $ Read more hereâ $ ¦

«The problem with HIV is that it is an extraordinarily hypervariable virus,» says Gregory Poland, a vaccinologist at the Mayo Clinic in Rochester, Minnesota.

A segment with cnvType «- «is called for the sequenced genome in a region where the reference set genomes display hypervariable characteristics.

The B2 haplogroup has been observed at low frequency among Southwest Native Americans based on hypervariable region sequences22.

Wolfiness queries a number of SNPs that we know are hypervariable between dogs and wolves.

We use morphometrics, allozyme electrophoresis, mitochondrial DNA (mtDNA) restriction - site analysis, and analysis of hypervariable minisatellite DNA to measure variability within and distances among island fox populations.

We also compared mitochondrial sequence diversity in the Malagasy with a manually curated database of 19,371 hypervariable segment I sequences, incorporating both published and unpublished data.

We investigated the distal gut bacterial communities of three healthy humans before and after treatment with ciprofloxacin, obtaining more than 7,000 full - length rRNA sequences and over 900,000 pyrosequencing reads from two hypervariable regions of the rRNA gene.

The latter seems connected to a «dopamine D4 receptor, which contains a hypervariable coding in its third exon.»

Hypervariable regions may result from sequencing artifacts or high copy repeat regions (such as STRs or segdups) with high degree of polymorphism.

If, in a different sequenced genome, the coverage is not well separated from the reference genomes, the region would be assigned «hypervariable».

A hypervariable region is called when coverage is highly variable across many genomes, including the sequenced genome, without appreciable clustering.

Figure 3 illustrates an example of a region that could potentially be called «hypervariable» in some genomes and cnvType «+» or «- «in other genomes.

Segments labeled «hypervariable» indicate that coverage does not support normal ploidy but coverage is highly variable across the sequenced genome and the 52 reference genomes and is without appreciable clustering.

The red called - segment line marks a region where the lack of sharply separated clusters is considered grounds for assignment of «hypervariable» region.

We are also not yet able to accurately detect changes in key regions of the Plasmodium genome including, for example, the hypervariable var genes, which contribute to the parasites» ability to evade our immune system.