Sentences with phrase «hypervariable regions»
We investigated the distal gut bacterial communities of three healthy humans before and after treatment with ciprofloxacin, obtaining more than 7,000 full - length rRNA sequences and over 900,000 pyrosequencing reads from two hypervariable regions of the rRNA gene.
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Hypervariable regions may result from sequencing artifacts or high copy repeat regions (such as STRs or segdups) with high degree of polymorphism.
The reliability and stability of these methods were described by Wu et al. 27 Illumina tag sequencing of the 16S rRNA gene V4 - V5 hypervariable region was performed at the Marine Biological Laboratory in Woods Hole, Massachusetts, using established methods.28, 29 Details of sequencing methods, quality control and filtering, and statistical modeling are presented in the eAppendix in the Supplement.
A hypervariable region is called when coverage is highly variable across many genomes, including the sequenced genome, without appreciable clustering.
The B2 haplogroup has been observed at low frequency among Southwest Native Americans based on hypervariable region sequences22.
Not exact matches
Region of SIV env that corresponds to the hypervariable V3 loop of HIV - 1.
If, in a different sequenced genome, the coverage is not well separated from the reference genomes, the region would be assigned «hypervariable».
The red called - segment line marks a region where the lack of sharply separated clusters is considered grounds for assignment of «hypervariable» region.
We are also not yet able to accurately detect changes in key regions of the Plasmodium genome including, for example, the hypervariable var genes, which contribute to the parasites» ability to evade our immune system.
All the samples were sequenced for the three hypervariable segments of the mitochondrial DNA (mtDNA) control region to assess the genetic composition of modern Mongolia.â $ Read more hereâ $ ¦
Neutrophil - specific DNA methylation hypervariable sites are enriched at dynamic chromatin regions and active enhancers.