Martin Maripuu, doctoral student at the Department of Clinical Sciences, Division of Psychiatry, has studied the correlation between low cortisol levels, so - called
hypocortisolism, and poor psychiatric and somatic health
in patients with recurrent depressions or bipolar disorder.
But not
in a) someone who is both stressed and leptin resistant, since increased leptin levels from the re-feed might not be powerful enough to offset other excitatory pathways b) someone who is currently emerging from yo - yo dieting or caloric restriction c) someone who is dealing with an over-stimulated appetite, d) someone experiencing stress, e) someone who has had a history of insomnia, f) someone who is underweight, since they have low leptin levels, g) anyone who has ever had an eating disorder, particularly bulimia or binge eating disorder or h) anyone with HPA axis or endocrine dysregulation, particularly women, including overt stress, hypogonadism, hypothalamic amenorrhea, hypercortisolism, or
hypocortisolism (adrenal fatigue.)