Sentences with phrase «hypothalamic insulin»

The authors demonstrated that hepatic and adipose insulin effects were disturbed as a secondary effect to hypothalamic insulin resistance (265).

Central hypothalamic insulin signaling interfered with negative feedback to the hypothalamus - pituitary - adrenal (HPA) axis in stressed male mice (151), which potentially explains high comorbidity rates of mental and metabolic disorders (see section V.P).

Binge drinking induces whole - body insulin resistance by impairing hypothalamic insulin action

Not exact matches

Growth hormone release - inhibiting hormone (somatostatin), a hypothalamic peptide that inhibits the release of growth hormone and also the secretion of insulin glucagon, and gastrin, was found in the rat stomach and pancreas in a concentration similar to that in the hypothalamus, as measured by radioimmunoassay.

They then turned to neurochemical studies, including lactate, glutamate and glutamine metabolism, effects on the hypothalamic - pituitary - adrenal (HPA) axis through cortisol secretion, and neurotrophins such as brain - derived neurotrophic factor (BDNF), insulin - like growth factor 1 (IGF - 1), and vascular endothelial growth factor (VEGF).

Mice lacking insulin receptor in brain or on hypothalamic neurons display an array of metabolic abnormalities, however, the role of insulin action on astrocytes and neurobehaviors remains less well - studied.

These featured similar anorexigenic effects of intranasal insulin with decrease in meal frequency and total food intake together with comparable changes in hypothalamic gene expression (262, 264).

It's a good stressor, but it will impact the hypothalamic - pituitary - axis, sex hormone balance, and insulin levels.

The main theories behind PCOS include genetics, a misfiring of the Hypothalamic - Pituitary - Ovarian axis and a relationship between insulin and androgen.

In this program, you will learn how the female and male sex hormone cycles, insulin and cortisol relationship, and the hypothalamic - pituitary - thyroid axis impact recovery for common conditions treated in rehabilitation.

By this time, in addition to my PCOS label, I'd been diagnosed with adrenal fatigue, insulin resistance and pre-diabetes, and hypothalamic amenorrhea.

The lipocalin - type prostaglandin D2 synthase knockout mouse model of insulin resistance and obesity demonstrates early hypothalamic - pituitary - adrenal axis hyperactivity

First, depression has been linked to multiple biological abnormalities, including vascular pathologic changes, autonomic function changes, hypercoagulability, and hypothalamic - pituitary - adrenal axis hyperactivity.10 Evidence shows that depression in adulthood is linked to elevated risk of developing cardiovascular disease, diabetes, and dementia in later life.11 Second, inflammation contributes to atherosclerosis, insulin resistance, and neurodegeneration.12 - 14 Evidence shows that elevation in inflammation biomarkers, such as C - reactive protein (CRP), in adulthood predicts the development of cardiovascular disease, diabetes, and dementia in later life.15 - 17 Third, metabolic abnormalities such as obesity, dyslipidemia, glucose intolerance, hypertension, and cardiorespiratory fitness contribute to vascular lesions and hormonal imbalance.