Sentences with phrase «hypothalamic neurons»

Objective: Dietary proteins are sensed by hypothalamic neurons and strongly influence multiple aspects of metabolic health, including appetite, weight gain, and adiposity.

The mice without an adipocyte clock and shifted feeding rhythms developed obesity, as well as changes in the relative amounts of various TGs stored in adipocytes, circulating in the plasma, and present in hypothalamic neurons associated with energy balance (31).

To explain the less commonly researched «discomfort when hungry» phenomenon, researchers at the Howard Hughes Medical Institute (HHMI) Janelia Research Campus hypothesized that specific hypothalamic neurons stimulate food - seeking behaviors to eliminate the negative feelings associated with energy deficit.

Mice lacking insulin receptor in brain or on hypothalamic neurons display an array of metabolic abnormalities, however, the role of insulin action on astrocytes and neurobehaviors remains less well - studied.

Results: A neurochemically diverse subset of both mouse and human hypothalamic neurons responded rapidly to l - leucine.

Leptin has influence on the activity of several hypothalamic neurons, and respectively — the formation of anorexigenic and orexigenic neuropeptides.

For example, one research found that chronic ethanol treatment in rats elevated TRH messenger RNA (mRNA) in hypothalamic neurons.

This oxytocin is in fact produced by the hypothalamic neurons and reaches the posterior pituitary gland through their axons.

Methods: We used primary cultures of post-weaning murine mediobasal hypothalamic neurons, hypothalamic neurons derived from human induced pluripotent stem cells, and calcium imaging to characterize rapid neuronal responses to physiological changes in extracellular l - Leucine concentration.