Primary testicular failure Klinefelter syndrome Cryptorchidism Orchitis Trauma HIV / AIDS Myotonic muscular deficiency Retroperitoneal fibrosis Aging Hypogonadotropic hypogonadism Kallman syndrome Prader - Willi syndrome Idiopathic hypopituitarism Pituitary tumors Suprasellar tumors Hemochromatosis Inflammatory, traumatic, vascular lesions of pituitary and
hypothalamus Obesity Severe chronic illnesses Medication Andropause
Not exact matches
Most provocatively, the leptin receptor is expressed strongly on neurons in those areas of the
hypothalamus that cause
obesity or leanness when destroyed.
In 1994, Jeffrey Friedman, Marilyn M. Simpson Professor and head of Rockefeller's Laboratory of Molecular Genetics, launched a new era in
obesity research by discovering a hormone called leptin, which acts on neurons in the brain's
hypothalamus region to suppress hunger.
He described a young boy with the sudden onset of
obesity who was eventually diagnosed with a lesion in the
hypothalamus area of the brain.
Restoring Serotonergic Homeostasis in the Lateral
Hypothalamus Rescues Sleep Disturbances Induced by Early - Life
Obesity