Follow - up studies in the mice could uncover more details about how a dysfunctional
hypothalamus leads to depression.
Not exact matches
Any suppression on the
hypothalamus can
lead to irregular periods.
Evolution has liberated human love from the reflexive neuroendocrine dominance of the
hypothalamus and instead has
led to mate choice and bonding based on relatively flexible motivation.
We specifically focused on the
hypothalamus because it is the brain region critical for regulation of homeostatic processes such as feeding,» said
lead author Sebastien Bouret, PhD, a member of The Saban Research Institute's Developmental Neuroscience Program and an associate professor of Pediatrics at the Keck School of Medicine of the University of Southern California (USC).
Dr Siddharth Banka, Clinical Senior Lecturer at the Manchester Centre for Genomic Medicine, who
led the study, explained: «Our team has identified that this new syndrome is caused by a small deletion on chromosome 6 that affects the function of
hypothalamus, a region of the brain that plays a number of important roles in the body.»
Although at an early stage, the researchers hope that the findings will help form part of a picture of how the
hypothalamus works and may
lead to new treatments in the future.
Patients lose certain brain cells in the
hypothalamus,
leading to a deficiency of hypocretin, a molecule that helps regulate the sleep - wake cycle.
It frequently
leads to blood sugar issues which dampen communication between the
hypothalamus, pituitary and thyroid glands.
Not only does high estrogen exposure cause men to grow boobs, it also affects the
hypothalamus and pituitary gland in the brain,
leading to decreased testosterone levels, reduced sperm count, reduced fertility and reduced libido.
However, the RAAS also has an affect on the
hypothalamus, which influences the neuroendocrine and limbic system
leading to heightened stress response and anxiety [32].
It's a problem with the hormone - producing gland — in this case, the
hypothalamus or the pituitary — that then causes the excess cortisol production at a very high level, and it
leads to a condition called Cushing's syndrome, which is also a pretty distinct disease entity.
Infusion of Brain - Derived Neurotrophic Factor into the Lateral Ventricle of the Adult Rat
Leads to New Neurons in the Parenchyma of the Striatum, Septum, Thalamus, and
Hypothalamus
An alternative mechanism involves heightened negative feedback sensitivity to glucocorticoids in the hippocampus following exposure to elevated cortisol levels early in development, which would inhibit CRH production in the
hypothalamus and, ultimately,
lead to lower cortisol levels over time (56).