Identification of these genes provides support for previously
hypothesized mechanisms of high - altitude adaptation and illuminates the complexity of hypoxia - response pathways in humans.
Not exact matches
What these scientists
hypothesize goes far beyond the realm
of cannibalism and into the very
mechanisms of evolution itself.
«Since urine formation and excretion by the kidney is one
of the most easily detectable rhythmic processes (we are forming and excreting much more urine during the day), we
hypothesized that at least a part
of this rhythmicity is dependent on the circadian clock
mechanism,» said Dr. Tokonami.
«The basic science question
of what causes these mounds has long existed, and the
mechanism we simulated has been
hypothesized.
«We
hypothesized that C. difficile must tightly control the production
of its iron acquisition
mechanisms so that just the right amount
of iron is brought into the bacteria,» said Ellermeier, who is an Associate Professor in the Department
of Microbiology, University
of Iowa, Iowa City.
Consulting the model, the researchers
hypothesized that the overall cell cycle's lack
of variation was the result
of a built - in negative feedback
mechanism.
We
hypothesize that the
mechanism of action
of J147 is related to its ability to increase the levels
of BDNF and NGF, and studies are being conducted to identify its molecular target.
Some
of the
hypothesized mechanisms that contribute to weight loss on the ketogenic diet include increased metabolism from the thermic effects
of the high protein levels and reduced appetite from the high satiety effect
of protein.
Piche et al (14) observed colonic fermentation — mediated lower esophageal sphincter relaxation, and they
hypothesized that a neural
mechanism was responsible for the action
of SCFAs on muscular tone.
A study that looked at the
mechanism behind dietary fibers effect on the microbiome, they
hypothesized that «dietary fiber resists digestion in the small intestine, and enters the colon where it is fermented to produce [short chain fatty acids] that may enhance the healthy composition
of gut microbiota.»
They also
hypothesize that antibiotics may increase breast cancer risk because they inhibit key parts
of the immune system that protect against cancer, as well as anti-inflammatory
mechanisms.
''... it could be
hypothesized that PD is, at least in part, a type
of «segmental» aging, in which specific, localized, and accelerated aging
mechanisms, which for reasons at present largely unknown, markedly affect dopaminergic (DA) neurons in the pars compacta region
of the midbrain substantia nigra (SnPC).»
The researchers found that «1) ingestion
of a large number
of calories at one time (binge eating) impacts metabolic parameters even when total calories and macronutrients are appropriate for weight; 2) the timing
of energy intake is an independent determinant
of the diurnal rhythm
of leptin secretion, indicating a relatively acute affect
of energy balance on leptin dynamics; 3) the
mechanism of exaggerated insulin secretion after a binge meal remains to be determined, but may be related to the altered diurnal pattern
of leptin secretion; and 4) as most binge eating episodes in the population are associated with the ingestion
of excess calories, it is
hypothesized that binge eating behavior is associated with even greater metabolic dysfunction than that described herein.»
Both
of these
mechanisms could lead to more stable glucose patterns over time, which some have
hypothesized may result in reduced appetite and energy intake (76,77).
Moreover, two features
of this study — the analysis sample
of experienced teachers and Cincinnati's use
of peer evaluators — may increase the saliency
of these
hypothesized mechanisms.
The
hypothesized mechanism is analogous to that by which El Niño, the periodic warming
of the eastern and central Pacific Ocean, affects weather thousands
of kilometers away.
Now imagine if there was already a known
mechanism of IR scattering that reduced IR loss to space resulting in a heating effect, and that the particulars
of the
mechanism were well understood, and that the substances responsible for this
mechanism were very well known, and that we were increasing the concentration
of this substance quite dramatically, and that we we seeing temperature rises as had had been
hypothesized almost a century ago, and that some signs indicative
of this particular
mechanism for warming had been observed.
Some
mechanisms for that are
hypothesized, e.g. methane release from polar regions, increased melting
of Greenland leading to stopping the Gulf Stream, rapid reduction
of Arctic sea - ice and its positive feedback, collapse
of Antarctic ice shelves, loss
of the Amazon, large volcanoes, asteroid impacts, unexpected solar variation.
Consider this key sentence: «The (climate) forcing from changes in total solar irradiance alone does not seem to account for these observations, implying the existence
of an amplifying
mechanism such as the
hypothesized GCR - cloud link.»
The
hypothesized mechanism is provided by the absorption bands
of CO2 that are located near the peak
of the black - body spectrum at the mean temperature
of the Earth.
This is precisely the kind
of feedback
hypothesized for enhanced greenhouse except this now has a demonstrated physical
mechanism and is
of such importance we should walk through its function just to be clear.
Additionally, individuals from lower SES homes report more stressful events during their lifetime, and the biological response to stressors has been
hypothesized as one
of the underlying
mechanisms for health and cognitive disparities in relation to SES (Anderson and Armstead, 1995; Hackman and Farah, 2009; Noble et al., 2012a).
To explain this interrelation we
hypothesized the same
mechanisms indicated in Borkovec» model (2004) and Alloy and colleagues (2000), which states that ruminative worrying is a form
of emotional avoidance that plays a role in the maintenance
of anxiety in generalized anxiety disorder (GAD) and mood disorders.
As
hypothesized, the experiments demonstrated that improving parenting practices and reducing contacts with deviant peers served as mediating
mechanisms for reducing rates
of adolescent delinquency.
Retraining the addicted brain: A review
of hypothesized neurobiological
mechanisms of mindfulness - based relapse prevention.
Changes in parenting behaviour have now been shown in several studies to mediate the effects
of PMT with young children with conduct problems.15 This is a critical finding that goes to the core
of PMT, as improvement in parenting behaviour is
hypothesized to be the central
mechanism by which change in child behaviour occurs.
Re-Training the Addicted Brain: A Review
of Hypothesized Neurobiological
Mechanisms of Mindfulness - Based Relapse Prevention.
Hypothesized mechanisms aside, these findings suggest that support for PA may serve to ameliorate the potentially maladaptive effects
of permissiveness, underscoring the need for assessment and joint consideration
of both practices and styles.
The primary constructs within the
hypothesized framework are: (1) social position variables — characteristics that are used within societies to hierarchically stratify groups (race, gender, socioeconomic status); (2) parenting variables — familial
mechanisms that may influence African American adolescents well - being, perceptions
of competence, and attitudes towards others in various contexts (e.g., parenting practices and racial socialization messages); (3) racial discrimination — negative racially driven experiences that may influence feelings
of competence, belongingness, and self - worth; (4) environmental / contextual factors — settings and surroundings that may impede or promote healthy identity development (e.g., academic settings); and (5) learner characteristics — individual characteristics that may promote or hinder positive psychological adjustment outcomes (e.g., racial identity, coping styles).
For positive emotion differentiation, we expect a similar
mechanism to hold true in the sense that we
hypothesize that people low on positive emotion differentiation show larger increases in intrinsic motivation in response to the experience
of specific positive emotions than people high on positive emotion differentiation.
Hypothesizing that owner behavior relies on
mechanisms that originally evolved to promote parenting, we predicted that, similarly to parenting behavior, we would find various components
of owner behavior related to support, warmth and control.
Using constructs with mismatched sources
of data, we conducted a set
of latent growth mediational analyses to test
hypothesized mechanisms explaining change.