Sentences with phrase «hypoxia due»

To mimic the in vitro hypoxic response in vivo, we developed a xenograft model based on the hypothesis that with increasing xenograft sizes, there will be a parallel increase in hypoxia due to rapid cell proliferation and restricted blood supply to the xenograft cells.

Our son Silas was born 5 weeks prematurely, and suffered grave hypoxia due to complications during the delivery.

Not exact matches

The study shows that the optic nerve could be damaged due to hypoxia without a spike in eye pressure, a finding that could help unravel the details of glaucoma sufferers with normal eye pressure levels.

The high altitude transverse valleys of the Himalayan arc were among the last habitable places permanently colonized by prehistoric humans due to the challenges of resource scarcity, cold stress and hypoxia.

In most cases, hypoxia is caused by either a dysfunction of the retinal vasculature, as in diabetic retinopathy and retinal artery and vein occlusions, or it is due to a mismatch between nutrient supply and demand, as in the case of a retinal detachment, where the retina is separated too far from the choroid to receive sufficient oxygen.

We hypothesized that this may be due to altered cancer stem cell (CSC) activity resulting from increased tumor hypoxia.

The reason for these differential effects of hypoxia may be due to the complex regulation of HIF - 1α activities by various subunits, posttranslational modifications, and the presence and effects of coregulators, which are known to vary between different cell types (6).

This would bypass the potential adverse effects of hypoxia on the CSC fraction while limiting tumor progression due to the general vasculature effects.

Purine nucleotides (ATP and its precursors) lost due to ischemia, hypoxia, or genetic predisposition are replaced via the purine nucleotide pathway.

As the problem progresses, respiration difficulties due to the enlarged stomach and a loss of adequate blood flow through the heart (decreased cardiac function due to pressure on the large vena cava and hepatic veins that returns blood to the heart) result in hypoxia (inadequate oxygen), shock and collapse.

These include eastern boundary current upwelling systems such as those off the U.S. west coast along coastal California, Oregon and Washington, deep - sea and subsurface oxygen minimum zones, and coastal waters that are already experiencing excess nutrient levels (eutrophication) and low dissolved oxygen (hypoxia) due to human - driven nutrient pollution from land - based activities.

The lower Chesapeake Bay is especially at risk due to high rates of sinking land (known as subsidence).96 Climate change and sea level rise are also likely to cause a number of ecological impacts, including declining water quality and clarity, increases in harmful algae and low oxygen (hypoxia) events, decreases in a number of species including eelgrass and seagrass beds, and changing interactions among trophic levels (positions in the food chain) leading to an increase in subtropical fish and shellfish species in the bay.66

«We find that climate change will move the onset of hypoxia ~ 7 days earlier, while also decreasing oxygen in the bay primarily due to increased temperature.

We represent people who have suffered any type of injury or illness due to failure to diagnose or misdiagnosis, from cancer to heart disease / hypertension to infection to the consequences of hypoxia (oxygen deprivation).

Brain damage due to lack of oxygen (hypoxia) caused by umbilical cord compression or strangulation.

Hypoxia and hypoxic - ischemic encephalopathy often occurs during childbirth due to various reasons, but the underlying cause is often the direct result of medical malpractice or negligence by the obstetrician (OB / GYN), nurse, midwife, doctor, or other medical professional.

If left untreated this can lead to coma and then death — usually due to hypoxia (oxygen deprivation).