Sentences with phrase «hypoxia in»

And yet we've seen the seasonal appearance of hypoxia in 6 of the last 6 years.

This leads to long - term scar tissue and hypoxia in a lesion that does not get any better.

Canine: Determination and Mapping of Acute and Chronic Hypoxia in Canine Tumors D08CA - 077, Marlene L. Hauck, Grant Amount: $ 113,230

Protection from Perinatal Hypoxia: In an August 2007 study published in British Journal of Obstetrics and Gynaecology, researchers examined the effect of magnesium supplementation and the development of hypoxic - ischaemic encephalopathy (HIE) or Perinatal hypoxia in babies.

Read the original research article here — «Genetically based low oxygen affinities of felid hemoglobins: lack of biochemical adaptation to high - altitude hypoxia in the snow leopard.».

Cheng C, Edin NF, Lauritzen KH, Aspmodal I, Christoffersen S, Jian L, Rasmussen LJ, Pettersen EO, Xiaoqun G, Bergersen LH (2012) Alterations of monocarboxylate transporter densities during hypoxia in brain and breast tumour cells Cell Oncol (Dordr), 35 (3), 217 - 27 PubMed 22700320

Large - scale transcriptional response to hypoxia in Aspergillus fumigatus observed using RNAseq identifies a novel hypoxia regulated ncRNA.

HIF - 2α expression regulates sprout formation into 3D fibrin matrices in prolonged hypoxia in human microvascular endothelial cells.

Additionally, expression of these mRNAs was also assessed following 24 h of recovery from hypoxia in room air compared to that in retinas isolated from control animals exposed only to air (Figure 2).

Most of the genes that were upregulated during hypoxia in our study are not known to be controlled by HIF - 1.

Our results confirmed and extended previous observations that genes associated with hypoxia (specifically VEGF, Flk - 1, and EPO) are indeed elevated following hypoxia in the retina.

Harris et al. [2] also provided evidence of the presence of retinal hypoxia in the early stages of diabetes by showing that contrast sensitivity was improved when patients with early diabetic retinopathy were made hyperoxic.

«Despite recent alarm about inner - shelf hypoxia on the Oregon coast, there appears to be no hypoxia currently in the main channel of Coos Bay, and there is little evidence of past hypoxia in the estuary,» Sutherland and co-author Molly A. O'Neill wrote in their conclusion.

Continuous monitoring of breath for this set could alert a pilot to hypoxia in real time.

The history of hypoxia in the Chesapeake Bay since 1985 can be found at the EcoCheck website.

A leading researcher in developmental programming, Challis says this study opens the door to thinking about combating fetal hypoxia in humans with antioxidant therapy.

«Our study provides profound insight into the role of cellular hypoxia in FOP flare - ups and shows that cellular oxygen sensing through HIF - 1α is a critical regulator of the BMP pathway and heterotopic ossification in FOP,» Kaplan said.

Plan to shrink Gulf dead zone Environmental Protection Agency background on dead zones Hypoxia in the Gulf of Mexico

The research team demonstrated that even when produced directly in cells, this molecule still prevents the HIF - 1 signalling and the associated adaptation to hypoxia in these cells.

The production of the HIF - 1 inhibitor occurs in response to hypoxia in these cells.

«A lot of that is associated with oxygen minimum zones, hypoxia in the ocean, dead zones.

In animal models, exposure to cigarette smoke or nicotine during fetal development alters the expression of the nicotinic acetylcholine receptor in areas of the brainstem important for autonomic function, 28 alters the neuronal excitability of neurons in the nucleus tractus solitarius (a brainstem region important for sensory integration), 29 and alters fetal autonomic activity and medullary neurotransmitter receptors.30 In human infants, there are strong associations between nicotinic acetylcholine receptor and serotonin receptors in the brainstem during development.31 Prenatal exposure to tobacco smoke attenuates recovery from hypoxia in preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDS.

Arousal and ventilatory responses to hypoxia in sleeping infants: effects of maternal smoking

Not exact matches

We have previously described studies of pacing strategy using various experimental interventions, including faster and slower starts, higher temperatures, hypoxia, hyperoxia and altered energy substrate availability.1 We have proposed the presence of a complex, regulatory system that mediates changes to skeletal muscle motor unit activation and work rate in order both to optimise performance and prevent potentially harmful changes to homeostasis.

If the initial work rate and RPE are set in a feedforward or anticipatory manner as is suggested (B and C on fig 2), then the starting power output should be similar whenever exercise is performed at a given RPE, irrespective of experimental interventions, such as increased ambient temperatures, hypoxia and dietary interventions.

Homebirth is expected to cause a delay in diagnosis, delivery and / or transfer following an acute intrapartum event with rapidly developing hypoxia, acidosis and asphyxia.

But, as the mother of two children who have learning disabilities — my son who has a sort of diffuse mild dyslexia coupled with ADHD which made it worse, and a daughter with classical severe dyslexia — it would not surprise me in the least if intrapartum hypoxia is not discovered to be a major component.

A compressed umbilical cord can also lead to short episodes of fetal hypoxia, which involves the baby being deprived from oxygen in the womb and can lead to other health complications including death.

Touches to breasts also can provoke the uterus tone that will entail in turn a hypoxia of the baby, because of impossibility to get oxygen fully.

The prone or side sleep position can increase the risk of rebreathing expired gases, resulting in hypercapnia and hypoxia.54, — , 57 The prone position also increases the risk of overheating by decreasing the rate of heat loss and increasing body temperature compared with infants sleeping supine.58, 59 Recent evidence suggests that prone sleeping alters the autonomic control of the infant cardiovascular system during sleep, particularly at 2 to 3 months of age, 60 and can result in decreased cerebral oxygenation.61 The prone position places infants at high risk of SIDS (odds ratio [OR]: 2.3 — 13.1).62, — , 66 However, recent studies have demonstrated that the SIDS risks associated with side and prone position are similar in magnitude (OR: 2.0 and 2.6, respectively) 63 and that the population - attributable risk reported for side sleep position is higher than that for prone position.65, 67 Furthermore, the risk of SIDS is exceptionally high for infants who are placed on their side and found on their stomach (OR: 8.7).63 The side sleep position is inherently unstable, and the probability of an infant rolling to the prone position from the side sleep position is significantly greater than rolling prone from the back.65, 68 Infants who are unaccustomed to the prone position and are placed prone for sleep are also at greater risk than those usually placed prone (adjusted OR: 8.7 — 45.4).63, 69,70 Therefore, it is critically important that every caregiver use the supine sleep position for every sleep period.

In a recent systematic review, the pooled mean prevalence of head covering among SIDS victims was 24.6 % compared with 3.2 % among control infants.154 It is not known whether the risk associated with head covering is attributable to overheating, hypoxia, or rebreathing.

Deficient hypoxia awakening response in infants of smoking mothers: possible relationship to sudden infant death syndrome

Changes in serotoninergic receptors 1A and 2A in the piglet brainstem after intermittent hypercapnic hypoxia (IHH) and nicotine

But supporters of Oklahoma's plan argue that nitrogen - induced hypoxia — or a lack of oxygen in the blood — is a humane execution method.

Senator Charles Schumer, the Senate minority leader, has called on Congress to quickly pass the Harmful Algal Bloom and Hypoxia Research and Control Act, which he said would help combat the rise in toxic algae found in Long Island waterways.

Shahrara and her colleagues knew that a protein called CCL28 was found in the body under low oxygen conditions, or hypoxia.

«This follicular hypoxia triggers a cascade of biochemical changes in the cumulus cells.

(hypoxia inducible factor 1 alpha), a protein that acts as a sensor for oxygen and nutrients in many types of cancer.

Now we know that changes in RNA of the cumulus cells triggered by aging - induced hypoxia, are the key messengers.

The hypoxia - treated rodents lived more than 6 months, compared with about 2 months for untreated animals, Mootha and his colleagues report online today in Science.

Continuous hypoxia is not practical in people, and depriving cells of oxygen can also fuel cancer.

Deactivating the VHL gene makes animals react as if they're in a low - oxygen environment, also called hypoxia.

The potential benefits of hypoxia need to be carefully considered alongside potential harms, notes Stephen Archer, a cardiologist at Queen's University in Kingston, Canada.

Harris and Peter Ratcliffe, also at the IMM, discovered the genetic switches, which they call «hypoxia - responsive elements» (HREs), in segments of DNA known as regulatory genes.

«This research will help prepare astronauts for spaceflight and it improves our understanding of how muscles respond to long periods of inactivity in association with hypoxia.

It is important to note that another study from the research group (the PlanHab Project), looking at whole - body exercise, found that hypoxia did in fact aggravate the impairment caused by microgravity alone.

This suggests that the effects of hypoxia could be more significant during whole body exercise, in which the stress on the cardiovascular system is more pronounced.

According to Chan, most hypoxia - intolerant species engulfed in low - oxygen waters quickly move away.

In the right hand panel, the cells are grown in hypoxia and in the presence of doxyxyxlin, therefore the cyclic peptide inhibitor is produced and HIF - 1 is inhibited, as demonstrated by the absence of the red dotIn the right hand panel, the cells are grown in hypoxia and in the presence of doxyxyxlin, therefore the cyclic peptide inhibitor is produced and HIF - 1 is inhibited, as demonstrated by the absence of the red dotin hypoxia and in the presence of doxyxyxlin, therefore the cyclic peptide inhibitor is produced and HIF - 1 is inhibited, as demonstrated by the absence of the red dotin the presence of doxyxyxlin, therefore the cyclic peptide inhibitor is produced and HIF - 1 is inhibited, as demonstrated by the absence of the red dots.

To enable them to survive, adapt and grow in the low - oxygen or «hypoxic» environments, tumors contain increased levels of a protein called Hypoxia - inducible factor 1 (HIF - 1).