Sentences with word «hypoxic»

However, the offspring of these adults, when reared in hypoxic conditions showed less ability to regulate their oxygen uptake and were significantly smaller than those of normoxic parents, potentially because they were having to expend more energy simply to survive in those conditions.

In addition, temporal [17] and spatial [16,17] correlations between increased levels of HIF - 1α, the regulatory subunit of HIF - 1, and increased VEGF expression have been shown, indicating that HIF - 1 may control the expression of VEGF in the retina under hypoxic conditions.

In vivo model of hypoxic CSC effect.

When a baby is obstructed in labour at home, or born with hypoxic brain injury, the delay in transferring to a tertiary hospital may result in permanent severe disability that will persist for the rest of that person's life.

MFC number increased significantly after hypoxic culture in all ER - α — positive primary samples and cell lines (Fig. 1A).

A child born with hypoxic ischemic encephalopathy and cerebral palsy as a result of medical negligence.

Interestingly, Rho kinase inhibition under hypoxic conditions produced a more effective increase in chondrocyte - specific gene expression and synthesis of extracellular matrix components by HCS - 2 / 8 cells.

The irregular vasculature of solid tumors creates hypoxic regions, which are characterized by cyclic periods of hypoxia and reoxygenation.

In preclinical studies, hypothermia and anti-oxidant treatment with N - acetylcysteine (NAC) are neuroprotective following neonatal hypoxic ischemia in females, but less so in males.

Raising a child with a hypoxia - related birth injury (such as hypoxic - ischemic encephalopathy) can cost a small fortune.

To help explain these results, Band and his colleagues looked to the gene expression profiles obtained from their previous studies of blind mole - rats in hypoxic environments.

NR1, NR2C, and NR2D were significantly elevated in hypoxic retinas compared with controls; these results were in close agreement with the microarray results (Figure 4).

Their study showed that the protein neuropilin - 1 (Nrp1) is crucial for the localization of TAMs inside hypoxic tumor regions, which strengthens the pro-tumoral characteristics of TAMs.

The minor plaintiff is currently a 2 - year - old girl who suffers from hypoxic ischemic injury (HIE) resulting from the defendants» negligence.

Using training masks for hypoxic training have been found inefficient.

«It can stimulate the expression of PGC - 1α and mitochondrial biogenesis in the cardiac myocytes, and this process might provide a potential adaptive mechanism for cardiac myocytes to increase ATP output and minimize hypoxic damage to the heart [xvi].»

Their consumption of oxygen could create hypoxic zones and have «a serious influence on biodiversity at those times as well,»

A 2014 study in Physiological Reports showed that short - term hypoxic training may help prevent arteriosclerosis.

Tumour cells become hypoxic because the blood vessels supplying them with nutrients and oxygen are often weak, twisted and ineffective due to the rapid growth of the tumour.

She is the coauthor of several published papers involving hypoxic cell sensitization from that research project.

Key aspects of ischemia - reperfusion can be modeled by a Caenorhabditis elegans behavior, the O2 - ON response, which is suppressed by hypoxic preconditioning or inactivation of the O2 - sensing HIF (hypoxia - inducible factor) hydroxylase EGL - 9.

Addition of vitamin D to hypothermia and NAC following neonatal hypoxic ischemia improves functional outcomes and preserves brain volume in male rodents, report researchers at the Medical University of South Carolina (MUSC) in the September 1, 2017 issue of Neuropharmacology.

Adult offspring from chronically hypoxic pregnancies show enhanced myocardial contractility due to sympathetic dominance and NO - dependent endothelial dysfunction in peripheral resistance vessels.

However, only few studies showed or discussed the possibility of establishing irreversible phenotypes through cycling hypoxic exposure without genetic manipulation [41, 42].

It is unlikely that she sustained any permanent damage in what turned out to be a 2 minute hypoxic episode.

The largest hypoxic zone measured to date occurred in 2002 and encompassed more than 8,400 square miles.

From some of London's most energetic and vibrant streets, enter a sanctuary of total fitness — from hypoxic chamber to Natural Fitness Food, 75sqm of climbing wall to a suspended glass floor training area.

In order to overcome these problems, Dr. Kizaka - Kondoh and his colleagues at Tokyo Institute of Technology developed a novel, highly - specific, functional imaging probe that can detect hypoxic tumours with HIF activity, which is a hallmark of malignancy and poor prognosis.

Higher CH4 emission is likely explained by a higher supply of organic matter under more hypoxic conditions, where CH4 oxidation is less likely to occur.

However, in order to come close to achieving a reduced target hypoxic zone of 5,000 square kilometers (1930.5 square miles) by 2050, nitrogen levels would have to be brought to zero — a scenario that the researchers note in their paper is «not only considered unrealistic, but also inherently unsustainable.»

Long - term measured size of Gulf of Mexico hypoxic zone with 2011 forecast.

Cadherin - 22 is located on cell surfaces, allowing hypoxic cancer cells to stick together and migrate collectively as a group, said Uniacke.

In an earlier article, Jenkins showed that females with severe hypoxic ischemic injury benefit from a combination treatment of hypothermia and NAC, which provides the rate - limiting amino acid for the primary anti-oxidant in all cells.

By refusing (or forgetting) to dry off and wrap the baby, Rixa and her husband made a bad situation worse by adding cold stress to hypoxic stress.

A lab at UC San Diego School of Medicine is currently investigating possible interventions to help prevent and treat hypoxic kidney injuries for kidney transplant patients.

No significant differences were observed between HIF - 1α mRNA levels in control animals and hypoxic animals at any time point.

«New Trends in Hypothermia Treatment for Newborns Suffering from Acute Hypoxic Encephalopathy,» American Conference Institute's 13th Annual Advanced Forum on Obstetric Malpractice Claims (Distinguished Co-Chair), June 2014

University of Illinois researchers have developed a way to find hypoxic spots noninvasively in real time.