To detect novel changes in gene expression, we used a focused microarray platform to evaluate the expression profile of retinas from
hypoxic animals compared to that in retinas isolated from control animals exposed to room air.
Not exact matches
A focused oligonucleotide microarray of 1,178 genes, qRT — PCR of selected transcripts, and western analysis of hypoxia inducible factor - 1α (HIF - 1α) were used to compare retinas from the
hypoxic and recovery groups to control
animals that were not made
hypoxic.
Animals used for measurement of HIF - 1α mRNA and protein were made
hypoxic for variable durations, from 0.5 to 6 h, before sacrifice.
Resulting
hypoxic conditions would cause large extinctions, especially of water breathing
animals, which is what we find at the PETM.
4/23/2008 Researchers Link Master Regulator of Innate Immunity to the
Hypoxic Response Survival of all
animals depends on their ability to withstand microbial infections and adapt to fluctuations in oxygen concentrations.