Sentences with phrase «hypoxic culture»

N1 - ICD was increased in all ER - α — positive primary cells and lines following hypoxic culture (Fig. 3A).

We measured the expression of ALDH1 in cell lines following normoxic and hypoxic culture and, in support of the MFC and HFC data shown above, show increased ALDH1 - positive cell number in ER - α — positive lines and a contrasting decrease in ER - α — negative lines (Fig. 1D).

No significant differences were seen between the normoxic and hypoxic anoikis - resistant populations collected from MCF7 cells and a single significant gene change (PIP) was seen in T47D (Table 1) suggesting that the CSC - enriched population remains virtually unchanged following hypoxic culture and the increase in MFC, HFC, and tumor initiating cells is, therefore, due to expansion of the population, perhaps by increased symmetric self - renewal of the CSC or de-differentiation of early progenitor cells, rather than simply the acquisition of anoikis resistance in non-CSC.

Not exact matches

Hypoxic effect on adherent holoclone culture (C) and percentage ALDH1 - positive cells (D).

Comparison of the total population following hypoxic and normoxic culture showed significant gene changes in both ER - α — positive and negative lines (Table 1).

B, HIF1 siRNA was used to block the hypoxic response before mammosphere culture.