Sentences with phrase «hypoxic environments»

Professor Ali Tavassoli, who led the study with colleague Dr. Ishna Mistry, explains: «In an effort to better understand the role of HIF - 1 in cancer, and to demonstrate the potential for inhibiting this protein in cancer therapy, we engineered a human cell line with an additional genetic circuit that produces the HIF - 1 inhibiting molecule when placed in a hypoxic environment.

However, in a hypoxic environment, it is activated and initiates a series of events to combat physiological effects of low oxygen.

When contracting a working muscle during a set, the blood vessels that feed that muscle are compressed, thereby creating a hypoxic environment which stimulates anabolism.

«The hypothesis that higher intake of plant foods is beneficial to human health because this increases antioxidant defence against oxidative damage is logical in evolutionary terms, especially when we consider the relatively hypoxic environment in which humans may have evolved.

Not exact matches

Some autopsy data shows that infants of smokers have signs of established hypoxic - ischemic cellular injury in the brain and the heart which probably occurred in antenatal life, may have been caused by suboptimal placental function and may have been sub-clinical, but if the baby continues to be in a vulnerable environment exposed to post-natal passive smoking, this could affect autonomic nervous system function and lead to poor temperature control, and poor heart rate and respiration control.

To enable them to survive, adapt and grow in the low - oxygen or «hypoxic» environments, tumors contain increased levels of a protein called Hypoxia - inducible factor 1 (HIF - 1).

Band led a previous analysis of gene expression in blind mole - rats living in low - oxygen (hypoxic) environments.

«Our results are consistent with the oxygen levels shown to influence blue crab behaviors in both field and laboratory settings,» says Brill, and «support the idea that blue crabs are well adapted to the hypoxic conditions occurring in the estuarine environments they occupy.»

Lead author Rich Brill, a fishery biologist with NOAA's National Marine Fisheries Service and adjunct faculty at VIMS, says «The notion that blue crabs are relatively intolerant of oxygen - poor waters was counterintuitive, because this species often occupies estuarine environments that can become hypoxic even in the absence of human activities.»

In fact, prevention of excessive swelling is important because fluid that has escaped into the tissues from excessive swelling can create a low oxygen (hypoxic) environment that can lead to additional tissue damage and delay healing.