Sentences with phrase «hypoxic ischemia»
Hypothermia alone, the current standard of care, neuroprotects roughly 50 percent of newborns with moderate to severe hypoxic ischemia.
https://www.sciencedaily.com/
Addition of vitamin D to hypothermia and NAC following neonatal hypoxic ischemia improves functional outcomes and preserves brain volume in male rodents, report researchers at the Medical University of South Carolina (MUSC) in the September 1, 2017 issue of Neuropharmacology.
Jenkins and her team plan to build upon these results with preclinical and clinical studies aimed at understanding the injury mechanisms underlying hypoxic ischemia and how they differ in males and females.
«Multi-mechanism approach to treating neonatal hypoxic ischemia: Vitamin D added to N - acetylcysteine and hypothermia following neonatal hypoxic ischemia improves functional outcomes, particularly in males.»
In preclinical studies, hypothermia and anti-oxidant treatment with N - acetylcysteine (NAC) are neuroprotective following neonatal hypoxic ischemia in females, but less so in males.
Not exact matches
Key aspects of ischemia - reperfusion can be modeled by a Caenorhabditis elegans behavior, the O2 - ON response, which is suppressed by hypoxic preconditioning or inactivation of the O2 - sensing HIF (hypoxia - inducible factor) hydroxylase EGL - 9.