Sentences with phrase «hypoxic pregnancies»
We investigated the effects of treatment of maternal hypoxic pregnancies with an antioxidant on the cardiovascular system of the offspring at two stages of life: in the fetal period at the end of gestation and at 4 months of adult age.
http://journals.plos.org/
These changes were not seen in newborn and adult offspring of hypoxic pregnancies treated with vitamin C, the team reports online today in PLoS ONE.
To test this idea, the team ran an experiment with four groups of pregnant rats: two sets undergoing hypoxic pregnancy and two controls.
Rats born of hypoxic pregnancy with no vitamin C treatment showed increased thickening of the walls of the aorta — up to 170 % above normal — and molecular markers of disease, such as an increase in the heart's heat shock proteins, a signal of cardiac oxidative stress.
On day 6 of pregnancy, rats were randomly divided into 4 groups (n = 20 per group): control and hypoxic pregnancy, with and without vitamin C treatment (5 mg.ml − 1 maternal drinking water freshly prepared every day).
Not exact matches
Melanocytes have the capacity to respond to a diverse number of extracellular signals, including UVR, endocrine signaling cascades that occur during pregnancy, micro-environments of the stem cell hair bulge vs. differentiated hair follicle niches, and hypoxic conditions found in metastatic melanoma tumors.