Sentences with phrase «ia 6at»

Prothena announced the dosing of the first Phase Ia subject on April 8, 2014; they appear to have been successful in recruiting subjects and to have quickly derived favorable safety signals, as they announced the dosing of the first PD volunteer in the Phase Ib trial on July 31, 2014, «based upon safety and tolerability observed to date in the ongoing study in healthy volunteers.»

late stages of stellar evolution: white dwarfs, isolated and in interacting binary systems, stellar explosions on white dwarfs (novae and type Ia supernovae).

A phase Ia study has started in France in May 2016.

It is also unclear why results are not presented for the MDS - UPDRS Ia subscale or for cognition, which were both listed in the study protocol as secondary outcomes.

The clinical trial is open labelled for the phase Ia arm conducted in Tübingen, Germany and double blinded for the phase Ib conducted at the Institut de Recherche Clinique du Bénin, Benin.

In the 1980s astronomers began to use Type Ia supernovae as standard candles.

Type Ia supernovas that exploded when the universe was only two - thirds of its present size were fainter and thus farther away than they would be in a universe without dark energy.

One technique for measuring the expansion rate is to observe the apparent brightness of objects of known luminosity like Type Ia supernovas.

Such a strategy will require a better understanding of the molecular mechanisms of antibiotic resistance, so in this study, the researchers solved the crystal structure of the resistance enzyme aminoglycoside phosphotransferase (4)- Ia in complex with the aminoglycoside hygromycin B.

SDSS measured spectra of more than 930,000 galaxies and 120,000 quasars as well as mapping the structure of the Milky Way by taking spectra of 240,000 stars and finding Type Ia supernovae to help us measure the history of the expansion of the universe.

Supergiant luminosities are not as well known or uniform as the Type Ia supernovae, so astronomers prefer to use the Type Ia supernovae to derive the distances to the very distant galaxies.

In the 1980s, as observational technology improved, scientists further divided Type I supernovae into three subcategories: Type Ia (which contain silicon in their spectra), Type Ib (which contain helium) and Type Ic (which contain neither)[source: Swisburne University of Technology].

A Phase Ia Study to Assess the Safety and Immunogenicity of New Malaria Vaccine Candidates ChAd63 CS Administered Alone and with MVA CS.

«We needed both the nearby Cepheid distances for galaxies hosting Type Ia supernovae and the distances to the 300 more - distant Type Ia supernovae to determine the Hubble constant,» Filippenko said.

This allowed them to improve the accuracy of the derived distances of these galaxies, and thus to more accurately calibrate the peak luminosities of their Type Ia supernovae.

Type Ia supernovae work differently than all other types.

Type Ia supernovas are known to form when a white dwarf merges with another star, like a puffed - up red giant (as opposed to Type II supernovas, which form when a single star dies and collapses on itself).

«Until now, the formation of supernovae Type Ia by the merging of two white dwarfs was purely theoretical,» said David Jones, one of the paper's coauthors who was an ESO Fellow at the time the data were obtained.

A Type Ia supernova results from a white dwarf that's part of a binary system (that is, one that shares an orbit with another star) and was about twice the size of our sun during its life.

Type Ia supernovae, another commonly used cosmic yardstick, are exploding stars that flare with the same intrinsic brightness and are brilliant enough to be seen from much longer distances.

And by using Type Ia supernovae as standard candles, researchers have been able to map entire galaxies» distances from us and determine that the universe is expanding ever more rapidly [source: Cal Tech].

By measuring about 2,400 Cepheid stars in 19 nearby galaxies and comparing the apparent brightness of both types of stars, they accurately determined the true brightness of the Type Ia supernovae.

The mass of the merged star will be enough to create a thermonuclear explosion, creating a type Ia supernova, the researchers said.

«It will have important repercussions for the study of supernovae type Ia.»

All Type Ia supernovas are thought to burn with equal brightness, making them so - called «standard candles.»

They then used this calibration to calculate distances to roughly 300 Type Ia supernovae in far - flung galaxies.

Binding of immunogenic peptides to Ia histocompatibility molecules.

It's so consistent that Type Ia supernovae are also called standard candles: Once astronomers find one in a region of space, they can use it as a baseline with which to compare other objects around it.

The blue «X» denotes the location of supernova 2003du, a Type Ia supernova.

Type Ia supernovae completely destroy the core of a star, but the other three types leave a super-dense core behind.

The stars are gradually drawing closer to each other and are expected to merge in about 700 million years, creating a Type Ia supernova

April 23, 2018 Ultragenyx Announces Filing and FDA Clearance of an Investigational New Drug Application for DTX401, a Gene Therapy for the Treatment of Glycogen Storage Disease Type Ia

Astronomers thought that all Type Ia supernovas shine with the same brightness, making them incredibly useful cosmic yardsticks.

Saul Perlmutter, Brian Schmidt and Adam Reiss share the 2011 Nobel Prize in Physics for their observations that type Ia supernovae indicate that the expansion of the universe is accelerating.

«We think most of the iron came from a single type of supernovae, called Type Ia supernovae,» said former KIPAC member and co-author Aurora Simionescu, who is currently with the Japanese Aerospace Exploration Agency as an International Top Young Fellow.

The researchers believe that at least 40 billion Type Ia supernovae must have exploded within a relatively short period on cosmological time scales in order to release that much iron and have the force to drive it out of the galaxies.

The discovery of a surviving companion would put an end to the ongoing discussion about the origin of type Ia supernova.

«The evidence has been building for years that the classical paradigm, the single - degenerate scenario, is not enough to explain every type Ia that we see,» Howell says.

If the stars merge with one another it would ultimately lead to a supernova explosion of type Ia.

When stellar cataclysms known as type Ia supernovae flare up far across the universe, their brightness and consistency allow astronomers to use them as so - called standard candles to measure cosmological distances.

In finding that the universe is on a path to runaway expansion, you had to find type Ia supernovae, which can act as distance markers.

But a new study presents evidence that, for at least one kind of galaxy, the binary - accretion model should not be more than a minor contributor to the observed type Ia supernovae population.

A group of astronomers used Hubble to study the remnant of the Type Ia supernova explosion SNR 0509 - 68.7 — also known as N103B (seen at the top).

A type Ia supernova arises from the explosion of an ultradense stellar remnant known as a white dwarf, but it is less than clear how the white dwarf comes to ignite in a thermonuclear blast.

And Gilfanov says that resolving the underlying astrophysics of type Ia supernovae would help make standard - candle measurements more precise.

Gilfanov says they are now working on characterizing the type Ia progenitors in other galactic types, such as the spiral cousins of our own Milky Way.

Type Iax supernovae are fainter than their type Ia relatives, which are so reliably bright that we use them as «standard candles» to estimate cosmic distances.

Andrew Howell, a staff scientist with the Las Cumbres Observatory Global Telescope Network in Santa Barbara, Calif., says that alternative origins for type Ia supernovae are becoming more compelling.

Just over a decade ago, two teams used the supernovae to show that the universe is accelerating in its expansion due to the influence of dark energy, a shocking discovery that thrust type Ia supernovae into the astrophysical limelight.

The predictable luminosity of Type Ia supernovae means that astronomers can use them as cosmic standard candles to measure their distances, making them useful tools in studying the cosmos.