Sentences with phrase «ips cell technology»

â $ œAlthough iPS cell technology has enormous potential for biomedical research and cell - based therapy, it is still in its early stage and significant obstacles must be overcome in order to realize its full potential.

This iPS cell technology represents an entirely new platform for fundamental studies of developmental biology.

«It is extremely gratifying to see iPS cell technology applied in humans only eight years after its discovery,» says Shinya Yamanaka, MD, PhD, a senior investigator at the Gladstone Institutes and member of the Roddenberry Stem Cell Center at Gladstone.

«New therapies for ALS are urgently needed — and our creation of human models using iPS cell technology will hopefully deepen our understanding of how the disease develops — and lead to relevant therapies for patients,» said Senior Investigator Steve Finkbeiner, MD, PhD, who leads ALS research at Gladstone.

Like them, I am optimistic that iPS cell technology will help find new solutions for those suffering from this devastating disease.»

In today's study, Dr. Ding focuses on reprogramming skin cells into β - cells using existing iPS cell technology — but with a twist.

«This is, to our knowledge, the first demonstration that iPS cell technology can be used for the generation of patient - specific, disease - corrected cells,» says Belmonte.

The need for new drug compounds that can combat skeletal dysplasia has led the Noriyuki Tsumaki group at CiRA, Kyoto University, to consider iPS cell technology.

Using iPS cell technology, the scientists found that only cells harboring the FOP gene mutation would respond to Activin - A by significantly increasing their BMP signaling.

Researchers in Japan are meanwhile using iPS cell technology to pave the way to better drugs.

«The danger with all iPS cell technology is cancer.»

Not exact matches

In the June 2010 issue of Nature Medicine, in an interview with theBoston - based researcher, Daley tells how he further changed the focus of his work after Prof. Shinya Yamanaka of Kyoto University, who won the 2010 Kyoto Prize for advanced technology, made known his successes with iPS cells in 2007: «Once Yamanaka solved the problem, I turned around virtually my entire programme to take advantage of that breakthrough,» he says.

Core Research for Evolutional Science and Technology and Yamanaka iPS Cell Project, Japan Science and Technology Agency, Kawaguchi 332-0012, Japan.

Next, the scientists removed the Duchenne mutations in the iPS cells using a gene editing platform they developed that uses the CRISPR / Cas9 technology.

In response to a query from Science, Kyoto University's Center for iPS Cell Research and Application, which Yamanaka directs, issued a statement that reads in part: «Our university filed the world's first patent application associated with iPS [cell] technology and is now trying to acquire patent rights in many countries, including the UCell Research and Application, which Yamanaka directs, issued a statement that reads in part: «Our university filed the world's first patent application associated with iPS [cell] technology and is now trying to acquire patent rights in many countries, including the Ucell] technology and is now trying to acquire patent rights in many countries, including the U.S..

In fertility clinics, iPS cells could enable prospective parents to choose embryos for desired traits more easily than they can with conventional assisted - reproduction technologies.

The mice show many of the symptoms that human patients do, and so they were an especially good candidate to test iPS cells» abilities, says stem cell researcher Rudolf Jaenisch of the Whitehead Institute for Biomedical Research and the Massachusetts Institute of Technology, both in Cambridge, who collaborated with Townes on the project.

Earlier this year, scientists at University of California, Los Angeles, and Advanced Cell Technology of Marlborough, Massachusetts, reported in The Lancet about the safe and successful use of RPE cells derived from human embryonic stem cells, rather than iPS cells, to treat a different type of AMD in a limited number of human patients.

«During the next 10 years,» says Svendsen, «we're going to see a trend away from using animals for disease modeling and using human cells with iPS technology instead.»

«This collaboration combines Dr. Yamanaka's human iPS cells and Novocell's hES cell differentiation and encapsulation technologies to explore the creation of next generation diabetes cell therapies,» said Emmanuel Baetge, Chief Scientific Officer of Novocell, Inc..

«I highly respect Novocell technologies and am pleased to collaborate with Novocell and explore the potential of their hES cell to islet cell advances in combination with our iPS cells as a potential new sources for the generation of cellular models and therapies for diabetes,» said Dr. Yamanaka, Director of Center for iPS Research and Application at Kyoto University.

Lanza, the chief scientific officer at Advanced Cell Technology, and colleagues shared the optimism about iPS cells.

Daley and other scientists are using iPS technology to reprogram cells from patients with diseases such as Lou Gehrig's disease (amyotrophic lateral sclerosis), Huntington's disease, and diabetes.

Many investigators, including those at Emory, are using the technology to establish â $ œdisease in a dishâ $ models and derive iPS cells from patient donations, turning them into tools for personalized medicine research.

At least one biotech company (iPierian) has been founded to exploit the commercial potential of these reprogramming technologies, and the Japanese government has established an entire research institute dedicated to fundamental and applied iPSC research (Center for iPS Cell Research and Application, Kyoto University).

Technology utilizing human induced pluripotent stem cells (iPS cells) has enormous potential to provide improved cellular models of human disease.

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