Not exact matches
They then tried to reprogram skin
cells from the animals, turning them into induced pluripotent
stem cells (
iPS), which are capable
of forming other
types of cell.
At a press conference, Harvard officials also announced the establishment
of a new
iPS «core» lab at the Harvard
Stem Cell Institute to speed the development of the new cell types and their dissemination to researchers around the wo
Cell Institute to speed the development
of the new
cell types and their dissemination to researchers around the wo
cell types and their dissemination to researchers around the world.
Researchers also plan to modify the genetic set up
of induced pluripotent
stem cells (
iPS), which can be differentiated into specialized
cell types or tissues.
In a second study, they applied CellNet's teachings to a recurring question in
stem cell biology: Is it feasible to directly convert one specialized
cell type to another, bypassing the laborious process
of first creating an
iPS cell?
These
stem cells — known as induced pluripotent
stem cells or
iPS cells — can be turned into almost any specialised
cell type of the human body, including the
cells we need to see.
When the researchers measured gene activity, they found that the
iPS cells were more similar to the ES
cells they descended from than to each other, suggesting that the source
of the
cells explains many
of the disparities researchers had noted between the two
stem cell types.
Stem cell researcher Konrad Hochedlinger
of Harvard University, who last year reported using a safer
type of virus to generate
iPS cells agrees that «these papers are an important advance.»
Earlier this year, scientists at University
of California, Los Angeles, and Advanced
Cell Technology
of Marlborough, Massachusetts, reported in The Lancet about the safe and successful use
of RPE
cells derived from human embryonic
stem cells, rather than
iPS cells, to treat a different
type of AMD in a limited number
of human patients.
In this study, induced pluripotent
stem (
iPS)
cells, which have the potential to differentiate into any
type of cell in the body, were used to model the disease.
Furthermore, the generation
of induced Pluripotent
Stem (
iPS)
cells from an individual RP patient would enable the large - scale production
of the
cell types affected by the patient's disease.
Rather than reversing
cells all the way back to a
stem cell state before prompting them to turn into something else, such as in the case
of iPS cells, the researchers «rewind» skin
cells just enough to instruct them to form the more than 200
cell types that constitute the human body.
A decade later, scientists figured out how to generate another
type of all - purpose
cell from human skin, known as induced pluripotent
stem cells, or
iPS.
First created in 2007, human
iPS cells are a very recently created
type of stem cell with great potential.
In an apparent world first, Japanese researchers have succeeded in producing intestine from induced pluripotent
stem (
iPS)
cells in mice, which can develop into various
types of cells in the body.
In addition to
iPS cells derived from progeria - patients, the researchers successfully applied their method to adult mesenchymal
stem cells, which can differentiate into a variety
of cell types, including adipocytes, osteoblasts, chondrocytes, cardiomyocytes, and, as described lately, beta - pancreatic islets
cells.
The NIH is already funding the banking
of one
type of pluripotent
stem cell, the so - called induced pluripotent
stem (
iPS)
cell, and it makes economic and scientific sense for the NIH to also fund embryonic
stem cell banking and distribution.