While second - stage
results showed no significant differences between participants continuing to receive weekly doses of the active drug, those receiving biweekly doses and those shifted to placebo, Kimball notes that, since it is typical for the severity of HS symptoms to increase and
decrease and because the study protocol required treatment discontinuation for participants whose symptoms stopped responding to the drug, larger scale studies will be required to better define the
ideal length and frequency of treatment.
Reason # 6: Getting fat, intentionally or carelessly,
results in
decreased thyroid production — not
ideal, because thyroid is critical for fat loss.