Scientists ask the same question when genetically
identical cells in identical environments — monoclonal cells produced by a single ancestor that replicated — exhibit wildly different behaviors.
But compared to a homogeneous material like water or a magnet — or even a collection of
identical cells in a dish — cancer is a hot mess.
Sheltzer, who began his project in the laboratory of Dr. Angelika Amon at MIT and carried it to conclusion in his own research group at CSHL, placed two sets of otherwise
identical cells in culture dishes, side by side.
Not exact matches
I would seem to be
identical with the history of the assemblage of
cells that includes my neurons; my action,
in the same way, would seem to be
identical with everything that is happening
in my body while I perform it.
The maximum difference between load
cell output readings for repeated loadings under
identical loading and environmental conditions; the ability of an instrument, system, or method to give
identical performance or results
in successive instances.
• Loss -
In - Weight: The compact trapezoid shape is
identical to both the volumetric & gravimetric feeder with either a single high performance digital or analog load
cell.
In addition, there may be applications where the use of one's own stem
cells are needed, even if stem
cells from an
identical twin are available.
While all
cells in a specific organism share the
identical DNA sequence, only a fraction of those genes are activated
in a given
cell type.
Salk scientists and collaborators have shed light on a long - standing question about what leads to variation
in stem
cells by comparing induced pluripotent stem
cells (iPSCs) derived from
identical twins.
Several physical measurements, including electron microscopy, assured us that our product was a closed loop coiled tightly around the virus - DNA template and that it was
identical in size and other details with the replicative form of DNA that appears
in the infected
cells.
Two sperm
cells from the same father apparently fused with the egg, which then split
in the same way that typical
identical twins come about.
Another is how
cells in a single organism take on different functions despite having
identical genomes.
Each person can have about 100 million different receptors, referred to as their T
cell repertoire, with little overlap even
in identical twins.
The two postembryonic touch receptor neurons
in the nematode Caenorhabditis elegans arise from essentially
identical cell lineages and have the same ultrastructural features.
Since the algae reproduces by
cell division about once per day
in the laboratory, numerous genetically
identical cultures could be derived from the isolate.
The shape and chemical composition of these granules is
identical to organelles found
in cells called melanosomes; these being responsible for creating and storing the pigment melanin.
Importantly, these three developmental signatures were found
in distinct genetic clones —
cells with
identical patterns of genetic mutations — of tumor
cells.
In almost all organisms, every cell contains identical genes — it is a difference in gene activation that distinguishes a blood cell from a nerve cel
In almost all organisms, every
cell contains
identical genes — it is a difference
in gene activation that distinguishes a blood cell from a nerve cel
in gene activation that distinguishes a blood
cell from a nerve
cell.
Used as a counter electrode
in a dye - sensitized solar
cell, the material enabled the
cell to convert power with up to 6.8 percent efficiency and more than doubled the performance of an
identical cell that instead used an expensive platinum wire counter electrode.
The researchers have shown that it is possible to produce chromosome modifications
in human
cells that are genetically
identical to those observed
in leukemia and other types of human cancer.
The case presented
in the latest paper, published
in the journal Stem
Cell Reports, suggests that uneven growth of
identical twins could start during the early stages of preimplantation development.
The grubs chewed their way out before the ferns fossilized, but they left behind feces (dark dots
in photo), which, Labandeira found, contained resin - filled
cells identical to surrounding plant
cells.
In abnormal [PSI +]
cells, which are genetically
identical to normal
cells, the important protein clumps together, and the
cells are unable to grow under certain conditions.
Bacteria expressing enzyme
in one
cell (bright green), while genetically
identical cells do not, remaining protected from antibiotic onslaught; image courtesy of Yuichi Wakamoto / Neeraj Dhar / John McKinney Some strains of nasty bacterial infections, such as MRSA (methicillin - resistant Staphylococcus aureus), come loaded with resistance to antibiotics built right into their genes.
In 1957, developmental biologists first discovered that they could insert the nucleus of adult frog
cells into frog eggs and create dozens of genetically
identical tadpoles.
For example, he lumps together competition between genetically
identical cells and competition between alleles
in a population.
The
cells in our bodies can divide as often as once every 24 hours, creating a new,
identical copy.
In contrast, the immortalized fat
cells allow experiments to be repeated multiple times on
identical cells ensuring consistent, reproducible results.
Just as no two people possess the same genetic makeup, a recent study has shown that no two single tumor
cells in breast cancer patients have an
identical genome.
As with the previous experiment, all the transplanted
cells were genetically
identical to the mice
in which they were injected.
Previous studies
in mice have shown, however, that even genetically
identical iPS
cells can trigger an immune response after transplantation.
The development of each motor neuron was hardwired; each
cell was always born
in the same order and achieved the
identical shape.
In the new study, Mikhail Pogorelyy and colleagues from the Ecole normale supérieure in Paris, and the Shemyakin - Ovchinnikov Institute of Bioorganic Chemistry, Moscow, address this excess of T - cell clone sharing between genetically identical twin
In the new study, Mikhail Pogorelyy and colleagues from the Ecole normale supérieure
in Paris, and the Shemyakin - Ovchinnikov Institute of Bioorganic Chemistry, Moscow, address this excess of T - cell clone sharing between genetically identical twin
in Paris, and the Shemyakin - Ovchinnikov Institute of Bioorganic Chemistry, Moscow, address this excess of T -
cell clone sharing between genetically
identical twins.
The team used a statistical model of T
cell receptor formation to analyze receptor DNA sequences
in blood samples from adult pairs of
identical twins.
Mitosis, the cellular division that produces two genetically
identical daughter
cells, is perhaps the most fundamental process
in biology.
We have demonstrated that
in winter Helsinki, black
cells generate considerably more electricity than traditional
cells even though both
cells have
identical efficiency values,» she adds.
In patients undergoing stem
cell injection, the skin changes were essentially
identical.
In the new study, published yesterday in PLOS Biology, Heitman and colleagues set out to explore whether genetically identical, unisexually reproducing C. neoformans cells were using aneuploidy to generate offspring that differed from themselve
In the new study, published yesterday
in PLOS Biology, Heitman and colleagues set out to explore whether genetically identical, unisexually reproducing C. neoformans cells were using aneuploidy to generate offspring that differed from themselve
in PLOS Biology, Heitman and colleagues set out to explore whether genetically
identical, unisexually reproducing C. neoformans
cells were using aneuploidy to generate offspring that differed from themselves.
About half of melanoma patients harbor an
identical tumor - specific mutation
in the BRAF gene, which encodes a protein kinase that helps drive
cell growth.
In the current paper, knowing that MYC, a transcription factor that binds the genome through sites that are identical to the binding sites of BMAL1, the team hypothesized that aberrant MYC expression perturbs the clock by deregulating components of the circadian network in cancer cell
In the current paper, knowing that MYC, a transcription factor that binds the genome through sites that are
identical to the binding sites of BMAL1, the team hypothesized that aberrant MYC expression perturbs the clock by deregulating components of the circadian network
in cancer cell
in cancer
cells.
A cloning
in the biological sense, therefore, is a molecule, single
cell (like bacteria, lymphocytes etc.) or multi-cellular organism that has been directly copied from and is therefore genetically
identical to another living organism.
Two
cells growing side by side
in a petri dish can not be considered
identical.
This is the first direct evidence that
cells indeed have an ability to distinguish
identical copies of chromosomes and separate them
in a regulated manner.
But
in a process called asymmetric division, a
cell divides into two daughters that are not
identical — a skin stem
cell divides into another skin stem
cell and a regular skin
cell, for example.
The first primate clones made by somatic
cell nuclear transfer are two genetically
identical long - tailed macaques born recently at the Chinese Academy of Sciences Institute of Neuroscience
in Shanghai.
But
in a paper published
in the journal
Cell, researchers at the Koch Institute for Integrative Cancer Research at MIT reveal that aneuploidy alone can cause this significant variability
in traits,
in otherwise genetically
identical cells.
Stromal
cells that reside
in the lymph nodes throughout the body manufacture proteins
identical to those made by gut
cells and use them to train T
cells to ignore certain proteins.
The structure and composition of the erionite from both regions is practically
identical, and samples from each place cause mesothelioma - associated changes and inflammation
in cell culture and mouse lungs.
Josef Singer and Judith Fazekas, both lead authors of the study, discovered that a receptor frequently found on human tumor
cells (epidermal growth factor receptor or EGFR) is nearly 100 percent
identical with the EGF receptor
in dogs.
Brain
cells in those areas did not have
identical DNA.