Pleiotropy means one gene (or
identical gene pair, if recessive) gives rise to more than one disease or characteristic; Alaskan Malamute dwarfism / anemic blood disorder is another example.
Not exact matches
Researchers have found a
pair of twins who are
identical on the mom's side but who share half the
genes on the father's side.
But if a promising
gene shakes out of the fraternal study, it's simple enough to look for the same
gene in the
identical pairings.
He figured out how the
pairs of
genes interact to influence the organism, depending on whether the
pair have
identical or differing messages.
By examining twin
pairs — both monozygotic (
identical from same fertilized egg) and dizygotic (fraternal from separate fertilized eggs)-- UW researchers assessed the extent psychological distress is related to caregiving, or confounded by common
genes and environmental exposure.
The database was developed by
identical twin brothers, Obi Griffith, PhD, and Malachi Griffith, PhD, whose interest in
pairing drugs with
genes is as much personal as it is scientific.
The Swedish Twin Registry has enabled her to compare
identical twins, who share 100 % of their
genes, with fraternal twins, whose genetic makeups are no more similar to each other than any
pair of siblings.
One ZFN
pair was used to target both the human and rhesus macaque CXCR4
genes since the 24 bp target sequences are
identical.
After analysing the GCSE results of 5474
pairs of twins — 2008 of them
identical — the team found that
genes accounted for 52 per cent of the differences between exam scores.
Comparison of
genes on the sex - determining X and Y chromosomes indicates that the ancestor of human sex chromosomes first arose from an
identical pair of standard chromosomes approximately 240 to 320...
Beyond the genetic information contained in DNA, the researchers examined patterns of DNA methylation — a molecular modification to DNA that affects when and how strongly a
gene is expressed — across the genome in
pairs of
identical male twins.
Using
gene expression variance and discordance between genetically
identical MZ twin
pairs, we identify 137
genes with age - related changes in variance and 42
genes with age - related discordance between co-twins; implying the latter are driven by environmental effects.
It has also been observed that after one member of
identical twin
pairs gets Type 1 diabetes, there is only a 13 - 33 % chance of the second twin getting the disease, even though both twins have the same
genes.