Often, early
identification of cancer is the difference between life and death.
She is particularly interested in
the identification of cancer driver mutations, genes and pathways across tumor types and in the study of their targeted opportunities.
Such targeting and ease of
identification of cancer cells could allow oncologists to spot even tiny numbers of diseased cells in a biopsy sample.
The study results challenge the current paradigm of microarray data analysis and suggest that the new method may improve
identification of cancer - associated genes.
The identification of the cancer cell of origin has important clinical implications, as it enables doctors to detect malignancies earlier and predict tumor behavior more accurately.
Not exact matches
Proteocyte Diagnostics, a company with a unique test for early
identification of oral
cancers, announced today that it has officially joined MaRS» SVX (Social Venture Connexion).
Proteocyte Diagnostics Inc., a company with a unique test for early
identification of oral
cancers, today announced an investment by Freycinet Investments, made possible by MaRS» SVX (Social Venture Connexion) impact investing platform.
TORONTO, July 15, 2014 — Proteocyte Diagnostics, a company with a unique test for early
identification of oral
cancers, announced today that it has officially joined MaRS» SVX (Social Venture Connexion).
«NTP has not written a report which «concludes» that 4 - MEI «causes
cancer,» nor has NTP otherwise identified 4 - MEI as «causing
cancer» in the way that phrase is used by NTP and regulatory agencies with respect to the
identification of chemicals as posing a carcinogenic hazard.»
Dr. Peter Infante, a former director
of the Office
of Carcinogen
Identification and Classification at the Occupational Safety and Health Administration, called the NAS critique «arrogant» because «we don't know the mode
of action for most things that cause
cancer.»
They are working together to mesh her
identification of compounds that target tumors with runaway Ras activity and tumor data (analyzed by machine learning) to find patients who could benefit from these potential
cancer drugs.
The discovery that the
identification and biopsy
of the first lymph node to which a
cancer spreads (the sentinel node) can lead to more accurate diagnosis and treatment has revolutionised the management
of breast
cancer.
A new tracer can enable surgeons to make an accurate
identification of the sentinel node — the lymph node to which
cancer spreads first — and hence spare patients the post-operative complications that may be linked to the removal
of a group
of lymph nodes in the neck.
When the results were compared with studies in the literature using standard radiocolloid tracers the researchers found that the SN biopsy using tilmanocept provided a high
identification rate and low false negative rate for SNs, thus facilitating accurate prediction
of the spread
of the
cancer.
Much like the association between BRCA gene mutation and the risk for breast
cancer in women changed the approach to treatment / prevention, the
identification of the Kallikrein 6 gene region may change the course
of prostate
cancer care through a blood test developed by the Lunenfeld - Tanenbaum Research Institute.
Identification of a specific genetic mutation in patients with non-small-cell lung
cancer (NSCLC) helps clinicians select the best treatment option.
«Despite the
identification of circulating tumor cells (CTCs) and cell - free DNA (cfDNA) as biomarkers capable
of providing clinically relevant information in
cancer patients, at present their identification is not routinely used in clinical practice,» explains Silvia Morbelli, MD, PhD, of the IRCCS San Martino — IST National Cancer Research Institute and University of Genoa in Genoa,
cancer patients, at present their
identification is not routinely used in clinical practice,» explains Silvia Morbelli, MD, PhD,
of the IRCCS San Martino — IST National
Cancer Research Institute and University of Genoa in Genoa,
Cancer Research Institute and University
of Genoa in Genoa, Italy.
In the Journal
of Biophotonics and the Analyst they compared conventional procedures for colon
cancer identification with a novel method called label - free spectral histopathology.
«The
identification and initial validation
of a highly accurate 5 - gene pancreatic
cancer biomarker panel that can discriminate late and early stages
of pancreatic
cancer from normal pancreas and benign pancreatic lesions could facilitate early diagnosis
of pancreatic
cancer,» said co-senior author Roya Khosravi - Far, PhD, Associate Professor
of Pathology at BIDMC.
The
identification of dormant niches in basement membrane microvasculature and how those niches become metastatic in the neovasculature holds important implications for future breast
cancer therapies.
This analysis led to the
identification of several lncRNAs that are overexpressed in a particular subset
of ovarian
cancer, those that are thought to be the most aggressive.
His research interests include the molecular underpinnings
of cervical
cancer (including developing genetic screens), the
identification of the genetic determinants
of quantitative traits in humans, and the application
of massively parallel sequencing technology for understanding the genetics
of complex disease.
The discovery
of EBV paved the way for the
identification of other
cancer - causing viruses, including human papillomavirus (HPV), and hepatitis B.
The enrichment factor described how frequently
cancer associated genes were identified compared to the frequency
of identification that one could expect by pure chance.
-
Identification of anti-hypertension drugs as potential therapeutics against breast and pancreatic
cancer metastasis was a big surprise.
«The
identification of HPV - negative endometrial - like tumors confirms that not all cervical
cancers are related to HPV infection and that a small percentage
of cervical tumors may be due to strictly genetic or other factors,» noted Jean - Claude Zenklusen, Ph.D., director
of NCI's TCGA program office.
«
Identification of these variations has helped the family to better understand why their children developed
cancer and to plan for the future,» said co-author Kim Nichols, M.D., a member of the St. Jude Oncology department and director of the St. Jude Cancer Predisposition Div
cancer and to plan for the future,» said co-author Kim Nichols, M.D., a member
of the St. Jude Oncology department and director
of the St. Jude
Cancer Predisposition Div
Cancer Predisposition Division.
Much like mutation
of the gene BRCA marks people at risk to develop breast and ovarian
cancers,
identification of mutations in the gene ETV6 may allow doctors to predict the development
of ALL, allowing increased monitoring and in the future, perhaps strategies to prevent the disease.
Research fields are diverse, including basic research on cell proliferation, analysis
of tumour cells and tissues to detect gene mutations, and
identification of potential therapeutic targets in
cancer.
These guidelines affirm early
identification, treatment, and ongoing assessment for psychological distress as important aspects
of prostate
cancer survivorship care.
The
identification of patients with high - risk breast
cancer is key to knowing whether a patient will require only the removal
of the tumor by surgery or whether if she will need additional chemotherapy to make sure the removal
of breast
cancer cells.
Identification and functional validation
of proteins involved in tumorigenesis are essential steps toward advancing
cancer precision medicine.
The
identification of novel molecular targets for
cancer can be a challenge.
Dr. Cole's research interests include
cancer genomics and the
identification of molecularly targeted therapies for pediatric malignancies.
Technology such as this, scientists said, may have a promising future in the
identification and surgical removal
of malignant tumors, as well as using near - infrared light therapies that can kill remaining
cancer cells, both by mild heating
of them and generating reactive oxygen species that can also kill them.
The
identification of genes that are synthetically lethal in β - catenin - activated
cancer cells would provide new targets for therapeutic drug design.
Identification of oxidized protein hydrolase as a potential prodrug target in prostate
cancer.
Identification of those men at greatest risk for prostate
cancer development and progression would provide a means
of targeted screening, thereby reducing unnecessary testing, false positive tests, and the burden
of overdiagnosis and over treatment.
The team's
identification of a direct cooperation between these two
cancer genes paves the way for targeted treatments - not only in ALL, but also in other leukemias where JAK3 / STAT5 could cooperate with HOXA9.
Identification of proangiogenic TIE2 - expressing monocytes (TEMs) in human peripheral blood and
cancer.
Further research uncovered a broad spectrum
of cell surface stem cell markers (e.g., CD133, CD44, and CD24) that allow the
identification of CSCs in human solid tumors, including brain, breast, prostate, pancreas, liver, ovary, skin, colon
cancers, and melanoma (3 - 6)(Figure 1 based on 7).
In 1989, Vogelstein's
identification of p53 gene mutations in colon
cancer began a tide
of research linking alterations in the gene to other
cancers.
Identification of a human papillomavirus - associated oncogenic miRNA panel in human oropharyngeal squamous cell carcinoma validated by bioinformatics analysis
of the
Cancer Genome Atlas.
Joan is recognized «for his important contributions to understand the development
of cancer, in particular, why
cancers evolve with mutations that are poorly immunogenic, and also for the
identification of special hepatic reparative cells with low propensity to produce
cancer».
IRB Barcelona has named Joan Font - Burgada (Caldes de Montbui, Barcelona, 1977) winner
of the 2018 IRB Barcelona Alumni
of Excellence Award «for his important contributions to understand the development
of cancer, in particular, why
cancers evolve with mutations that are poorly immunogenic, and also for the
identification of special hepatic reparative cells with low propensity to produce
cancer,» states the report by the jury — a body formed by senior IRB Barcelona researchers with expertise across several fields
of research.
$ 1.8 M Supports
Cancer Drug Discovery on Commonly Mutated Gene New Brunswick Patch — April 5, 2016 Behavioral Scientist Shares Insights about FDA's Proposed Rule on Banning Tanning Bed Use among Minors News-Medical.net - March 19, 2016 Intervention Program Reduces Caregiver Distress during Hospitalization
of Pediatric Stem Cell Transplant Patients News-Medical.net - March 9, 2016 Exploring Genomic Pathways in the Development
of Ovarian
Cancer GMNews.com - March 2, 2016 Differences in Type
of Small Protein may further Elucidate Lung
Cancer Risk in African Americans ScienceDaily.com - March 2, 2016 Study Looks at Post-Treatment Resources for Prostate
Cancer Patients Transitioning to Survivorship News-Medical.net - February 11, 2016 Drawing the Line on Tanning Bed Use by Teens ScienceDaily.com - December 21, 2015 What Rutgers Study Uncovered about E-Cigarette Use NJBiz.com - December 9, 2015
Identification of Barrier that Prevents Progression
of Benign Kidney Tumors to Malignant Disease MedicalNewsToday.com - November, 24, 2015 What is the Color
of the Lung
Cancer Ribbon?
The characterization
of the genetic alterations observed in neuroblastoma led to the
identification of major players
of neuroblastoma oncogenesis that has considerably improved our understanding
of the biology
of this pediatric
cancer.
Understanding these pathways, and the
identification of the key proteins that control the ability
of cancer cells to reprogram their metabolism through biochemical, and epigenetic or genetic alterations that make them resistant to therapies, is
of paramount importance for the design
of more targeted and therefore less toxic therapies.
Identification of six new susceptibility loci for invasive epithelial ovarian
cancer.
The Conquer
Cancer Foundation is a public charity exempt from federal income tax under Section 501 (c)(3)
of the Internal Revenue Code and the organization's Federal
Identification Number (EIN) is 31-1667995.