Sentences with phrase «identification of drug»
This opens immense potential to shorten the sample - to - results time and is likely to lead to enormous benefits in rapid diagnosis of bacterial infection and identification of drug resistance.
https://nanoporetech.com/
My background was in the identification of drug targets in prostate cancer, so working on developing new therapies in glaucoma was a natural progression.
Our proprietary antibody discovery technology quickly characterizes every cell in complex immune systems, powering our selection of drug targets, identification of drug candidates and preclinical assessment of efficacy.
It can be used in the identification of drug targets and eventually in the development of efficient strategies for treating a number of chronic liver diseases.
Our industry - leading technology, invented by GigaGen's co-founders, interrogates immune systems with unprecedented depth and breadth — radically accelerating the selection of drug targets, identification of drug candidates and assessment of pre-clinical drug efficacy.
Mardinoglu says the team's network modeling approach, which relied on data from the Sweden - based Human Protein Atlas project and The Genotype - Tissue Expression (GTEx) project consortia, can be used in the identification of drug targets and eventually in the development of efficient strategies for treating a number of chronic liver diseases.
Selective 5 - hydroxytryptamine 2C receptor agonists derived from the lead compound tranylcypromine: Identification of drugs in several animal models of CNS related disorders.
Not exact matches
The company announced in September that Health Canada granted market authorization to formally transfer the Drug Identification Number (DIN) ownership of Belbuca (buprenorphine) buccal film in Canada to BDSI's commercial partner, Purdue Pharma in Canada.
The marketplace operated using the Tor network and is most commonly associated with the sale of drugs, false identification documents, and computer hacking software.
♦ There was editorial hustling here to get in at the last minute the proper identification of William Bennett to accompany his article on drugs and morality (December 1990).
Identification and quantification of drugs and drug metabolites in human breast milk using gas chromatography mass spectrometry computer methods.
Hazmat Team members practice with monitoring instruments used to aid in the identification of potentially hazardous materials in a mock clandestine drug lab.
Identification and development of novel drugs that can target beta - arrestin - 1 can be an important step in this direction.»
«Elucidation of essential pathways involved in the endosymbiosis... will allow for the identification of novel drug targets.»
They are working together to mesh her identification of compounds that target tumors with runaway Ras activity and tumor data (analyzed by machine learning) to find patients who could benefit from these potential cancer drugs.
From accelerating the identification and validation of novel therapeutic targets, to creating better animal models of human diseases in a shorter time frame, to reducing the number of failed products, Crispr looks set to shave millions off R&D costs and boost drug discovery, she says.
The Mast Cells and Basophiles: Targets for Innovative Therapies project, funded by COST funding BM1007 of the EU, brings together European experts focusing on the identification of new target molecules for drug development, including allergy drugs.
In the end, the identification of microbial species or metabolites that are altered in Parkinson's disease may serve as disease biomarkers or even drug targets, and interventions that correct microbial imbalances may provide safe and effective treatments to slow or halt the progression of often debilitating motor symptoms.
While the commercial potential might not be immediate, Duncan says the collaboration could yield concrete rewards for the companies, such as new R&D avenues from identification of novel drug targets.
Mathias Uhlen, director of the Human Protein Atlas project and co-author of the paper, says: «I am extremely pleased that the resource created through the Human Protein Atlas effort has been used in the analysis of clinical data obtained from liver disease patients and that this analysis has led to the identification of liver - specific drug targets that can be used for treatment of this clinically important patient group.»
Among this year's start - ups were Novolytics, which is developing antibacterial - resistance therapy, Exilica, which has produced silica nano shells for the slow release of chemicals for drug delivery (among other potential uses), and Blueprint Healthcare, which has developed a DNA - based pet identification service.
«The identification of these genes paves the way for the development of a test to identify individuals who are at risk of getting Fuchs dystrophy, and also for the development of drugs to slow disease progression or to potentially delay or prevent it from occurring,» said George A. McKie, D.V.M., PhD., director of the NEI's cornea research program.
As a result, the identification of the gene could also lead to the creation of drugs to suppress appetite and fight America's rampant obesity.
Dr. Seshadri, founding director of the Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases at UT Health San Antonio and holder of the university's Robert Barker Distinguished University Chair, said the identification of genetic regions that are strongly correlated to stroke will increase potential targets for stroke drug development.
The advance, described in next month's issue of Nature Biotechnology, could lead to more accurate screening of organ donors and identification of genetic targets for new drugs.
His current specific interest is the elucidation of novel mechanisms of drug resistance through the discovery / identification of novel gene function (s) and phenotypes using RNAi - mediated gene silencing or cDNA overexpression.
Identification of the alterations responsible for drug - related memories could open the door to treatment options for people with addiction.
- Identification of anti-hypertension drugs as potential therapeutics against breast and pancreatic cancer metastasis was a big surprise.
Indeed, their combined phenotypic screening and target - identification approach enabled them to quickly discover, characterize and carry out preclinical tests of a potential new drug for obesity - linked diabetes: a complex metabolic disorder that affects 347 million people worldwide.
«The discovery of an alternative binding site and the AAPs represents a significant step towards the identification of a novel RNAP inhibitor that would behave like rifampin but be devoid of any pre-existing resistance,» said Nader Fotouhi, Chief Scientific Officer at the Global Alliance for TB Drug Development, a not - for - profit organization dedicated to finding faster - acting and affordable drug regimens to fight drug sensitive and resistant tuberculoDrug Development, a not - for - profit organization dedicated to finding faster - acting and affordable drug regimens to fight drug sensitive and resistant tuberculodrug regimens to fight drug sensitive and resistant tuberculodrug sensitive and resistant tuberculosis.
Therefore, identification of molecules that affect both parasites during their release from infected host cells not only highlights robustness of the complementary screening approach we adopted, but also conserved drug targets for pan anti-parasitic drug development,» Dr Dhanasekaran Shanmugam from NCL added.
This discovery, recently published as a paper, «Mutual potentiation drives synergy between trimethoprim and sulfamethoxazole» in Nature Communications, has the potential to open new doors for identification of other synergistic drug combinations.
A better understanding of the process affected in the brain will lead to identification of new drug targets, and potentially, life - changing preventive therapies or treatments.
The identification of what happens in a rat's brain when it falls off the wagon «gives us a target against which we can work to find appropriate medications to deal with relapse,» says Alan Leshner, director of the National Institute on Drug Abuse in Bethesda, Maryland.
It will also provide diagnostic tools for disease identification and allow medical professionals to measure the effectiveness of drug treatment regimes in an easy laboratory manner.
Currently we are using this system for identification of novel therapeutic targets and for screening and characterization of the effects of anti-diabetic drugs.
«Our work allows us to probe the activity of heparanase in human samples — allowing early disease identification and a direct measure of the success of drugs in humans.
Genome - scale metabolic models as platforms for identification of novel genes as antimicrobial drug targets — Bashir Sajo Mienda — Future Medicine
Drug screening Identification of compounds with therapeutic potential for DM1 will be performed through the implementation of large - scale technological resources.
The identification of genes that are synthetically lethal in β - catenin - activated cancer cells would provide new targets for therapeutic drug design.
The Woodlands, Texas — May 11, 2006 — Lexicon Genetics Incorporated (Nasdaq: LEXG) announced today that it was awarded a grant from the United States Army Medical Research & Materiel Command (USAMRMC) for the identification of targets that may be important in the development of drugs to prevent or treat spinal muscular atrophy (SMA), a neurodegenerative disorder and the leading genetic cause of death in early childhood.
He has over 15 years of experience in various aspects of systems biology including network inference, biomarker discovery, patients» specific disease checkpoints, and drug target identification, drug repurposing and predicting compound synergy.
«If we can establish a link between abnormal forms of this gene and ADHD, it could provide us with a powerful new tool for precise diagnosis and early identification of children at risk, and a signpost toward designing better drug treatment,» said Ed Cook, associate professor of psychiatry and of pediatrics at the University of Chicago and lead author of the report.
$ 1.8 M Supports Cancer Drug Discovery on Commonly Mutated Gene New Brunswick Patch — April 5, 2016 Behavioral Scientist Shares Insights about FDA's Proposed Rule on Banning Tanning Bed Use among Minors News-Medical.net - March 19, 2016 Intervention Program Reduces Caregiver Distress during Hospitalization of Pediatric Stem Cell Transplant Patients News-Medical.net - March 9, 2016 Exploring Genomic Pathways in the Development of Ovarian Cancer GMNews.com - March 2, 2016 Differences in Type of Small Protein may further Elucidate Lung Cancer Risk in African Americans ScienceDaily.com - March 2, 2016 Study Looks at Post-Treatment Resources for Prostate Cancer Patients Transitioning to Survivorship News-Medical.net - February 11, 2016 Drawing the Line on Tanning Bed Use by Teens ScienceDaily.com - December 21, 2015 What Rutgers Study Uncovered about E-Cigarette Use NJBiz.com - December 9, 2015 Identification of Barrier that Prevents Progression of Benign Kidney Tumors to Malignant Disease MedicalNewsToday.com - November, 24, 2015 What is the Color of the Lung Cancer Ribbon?
El - Khodor, B. F.; Edgar, N.; Chen, A.; Winberg, M. L.; Joyce, C.; Brunner, D.; Suarez - Farinas, M.; Heyes, M. P. Identification of a battery of tests for drug candidate evaluation in the SMNDelta7 neonate model of spinal muscular atrophy.
Screening of FDA - approved Drugs and Identification of Novel Lassa Virus Entry Inhibitors — Peilin Wang — bioRxiv
The collaboration is based on expanding Pelago's CETSA technology capabilities and will enable screening of large chemical libraries for identification of novel chemical leads with high drug potential.
GigaGen's Surge technology interrogates natural immune systems with unprecedented depth and breadth, radically accelerating target selection, drug candidate identification and pre-clinical assessment of drug efficacy.
The identification of a common molecular pathway for regeneration raises the possibility that drugs could be developed to trigger the dormant molecular mechanism in humans.
It helps us understand the genetic basis of diversity and evolutions in organisms, leading to the insight understanding into how living things evolved through stressed environments to the pathogenesis of pathogens, including identification novel drug targets and development of novel drug candidates.