This review highlights key psychosocial factors to assist
the identification of patients at high risk of psychological distress.
Studies in other health care patient groups have already indicated that
identification of patients at risk for emotional problems is difficult for health care professionals.
For
the identification of patients with differences in coping resources, a cluster analysis was conducted.
Early
identification of patients with either major depression or milder depressive symptoms is therefore necessary, so that they can be appropriately managed.
Because lactate measurement offered no meaningful change in the predictive validity beyond 2 or more qSOFA criteria in
the identification of patients likely to be septic, the task force could not justify the added complexity and cost of lactate measurement alongside these simple bedside criteria.
This signature allows
the identification of those patients who have a high risk of developing metastasis and who, therefore, might benefit from adjuvant chemotherapy.
Metabolic profiling has been shown to improve
the identification of patients at increased risk for cardiometabolic events.
Identification of patients sharing variants in a given gene and having phenotypic features in common leads to greater certainty in the pathogenic nature of the gene and enables to the role of novel genes in development and disease to be defined.
Together, these resources will form a unique foundation for the discovery of pathogens and pathogenic mechanisms in CFS and
the identification of patients who will most likely respond to specific treatments.
Therefore, better
identification of patients at risk for aortic aneurysm and dissection is considered essential.
The identification of patients with high - risk breast cancer is key to knowing whether a patient will require only the removal of the tumor by surgery or whether if she will need additional chemotherapy to make sure the removal of breast cancer cells.
Early
identification of patients with risk factors for a number of disorders would allow for early treatment that could potentially stop the development of disease in its earliest stages.
The researchers point out that organised trauma care networks rely on correct and prompt
identification of patients with serious injury and emergency transport direct to a trauma care centre rather than the local hospital.
«Early
identification of patients more likely to experience end - stage kidney disease is an urgent, unmet clinical need,» Kretzler says.
Hippo Manager has added two noticeable icons to the top right corner of the patient reserve area to allow immediate
identification of a patient with an alert or, an allergy.
Mixes pharmaceutical preparations and IVs, affixes labels for proper
identification of patient and medications to IV bags or other packaging
Not exact matches
They demonstrated a range
of devices: a mobile ultrasound machine, a handheld air sensor, and a
patient identification necklace.
Citing a 2010 study finding that
patients who had at least two 2 rehabilitation visits for persistent dizziness after a concussion showed improvement in their DHI scores (2), the study said that on - field
identification of dizziness could lead to earlier implementation
of vestibular rehabiliation and other modalities to treat dizziness, which may expedite recovery from concussion.
Dr Vos said one
of the main reasons for success was search and destroy which involves the early detection, early
identification and early containment
of infection and encompasses
patients, healthcare workers and the healthcare environment.
The bill will go into effect immediately once signed, but registrant
identification and licenses for the five companies that will be permitted to grow and distribute medical marijuana won't be issued for roughly 18 months while the Department
of Health develops regulations, trains and certifies doctors and registers
patients.
Bellevue is designated for the «isolation,
identification and treatment
of potential Ebola
patients» in the city, the statement said.
The Governor has designated eight hospitals statewide to treat potential
patients with Ebola, the State Department
of Health has issued a Commissioner's Order to all hospitals, diagnostic and treatment centers, and ambulance services in New York State, requiring that they follow protocols for
identification, isolation and medical evaluation
of patients requiring care.
Draetta's team developed an in vivo platform called
Patient - based In vivo Lethality to Optimize Treatment (PILOT), a technology enabling systemic identification of tumor vulnerabilities in patient - derived
Patient - based In vivo Lethality to Optimize Treatment (PILOT), a technology enabling systemic
identification of tumor vulnerabilities in
patient - derived
patient - derived tumors.
In this special section
of Science, expert contributors retrace the long and tortuous path leading to the mapping and
identification of the BRCA1 gene; discuss the ways in which BRCA mutation status has been integrated into the clinical management
of patients in high - risk families; and highlight the role
of the BRCA proteins in preserving the structural and numerical integrity
of chromosomes throughout the cell cycle, a function that may explain their tumor suppressor activity.
The
identification of these biomarkers may help to track disease in pre-symptomatic
patients, and could help researchers develop strategies to remedy the biochemical abnormalities.
Last December, the same research team demonstrated blocking the expression
of the gene that encodes apoC - III led to major relief
of triglyceridemia in
patients suffering a rare and extreme form
of hypertriglyceridemia, which in turn opened the door for the
identification of unexpected mechanisms that govern blood fat.
They are working together to mesh her
identification of compounds that target tumors with runaway Ras activity and tumor data (analyzed by machine learning) to find
patients who could benefit from these potential cancer drugs.
Other researchers can apply the method to different sets
of patients with hospital - linked genomic records, and
identification of the same loci would strengthen the support for their role in psychiatric symptoms.
A new tracer can enable surgeons to make an accurate
identification of the sentinel node — the lymph node to which cancer spreads first — and hence spare
patients the post-operative complications that may be linked to the removal
of a group
of lymph nodes in the neck.
«If we find that lymphoscintigrams using tilmanocept are at least as good as the conventional radiocolloid tracer in
identification and visualization
of sentinel nodes, we would like to see a randomised clinical trial involving large numbers
of patients,» says Prof de Bree.
«We believe that we have made an important step forward in minimising post-operative complications for
patient with early HNSCC, enabling a more accurate
identification of the stage
of their disease, and reducing the cost to healthcare systems at the same time,» Prof de Bree will conclude.
Deep - sequence coverage allowed
identification of 263 iSNVs (73 nonsynonymous, 108 synonymous, 70 noncoding, and 12 frameshift) in the Sierra Leone
patients (6).
Novel 3D vascular ultrasound imaging technology allowed researchers to quantify the amount
of carotid artery plaque burden lining each
patient's carotid arteries in their neck, while a coronary artery calcium score CT scan allowed for the
identification of any narrowing or hardening
of the coronary arteries due to the buildup
of fatty cholesterol and calcified plaque.
«The
identification of a new inflammatory target in rheumatoid arthritis holds promise for better treatment for these
patients and perhaps those with other autoimmune or inflammatory diseases.»
The estimation
of EGFR mutation status is essential for the
identification of non-small cell lung carcinoma (NSCLC)
patients who may benefit from treatment with EGFR tyrosine kinase inhibitors (TKIs), and hence for improving therapeutic efficacy.
«We were very excited to find that the three
patients in whom the odor detection threshold was improved by more than 10 percent after theophylline treatment were also the top three in terms
of odor
identification improvement,» says Paunescu.
Identification of a specific genetic mutation in
patients with non-small-cell lung cancer (NSCLC) helps clinicians select the best treatment option.
In a group
of 9 such
patients, this analysis
of their DNA (and the DNA
of their parents) resulted in the
identification of 2
patients with de novo mutations in CHD2, which stands for chromodomain helicase DNA binding protein 2.
His program, Portland
Identification and Early Referral, or PIER, was a groundbreaking effort to find and treat
patients showing early warning signs
of psychosis.
«Despite the
identification of circulating tumor cells (CTCs) and cell - free DNA (cfDNA) as biomarkers capable
of providing clinically relevant information in cancer
patients, at present their
identification is not routinely used in clinical practice,» explains Silvia Morbelli, MD, PhD,
of the IRCCS San Martino — IST National Cancer Research Institute and University
of Genoa in Genoa, Italy.
Mathias Uhlen, director
of the Human Protein Atlas project and co-author
of the paper, says: «I am extremely pleased that the resource created through the Human Protein Atlas effort has been used in the analysis
of clinical data obtained from liver disease
patients and that this analysis has led to the
identification of liver - specific drug targets that can be used for treatment
of this clinically important
patient group.»
It will also allow for easier
identification of genes that contribute to the bacteria's spread from
patient to
patient, and more meaningful scientific experiments to understand the bug's resistance to antibiotics or identify new antimicrobial compounds that target specific genes necessary for maintaining these persistent infections.
«Because interventions to reduce the risk
of readmission for any group
of patients can be costly and labor intensive,
identification of the highest risk cohort for readmission can allow more targeted intervention for this population
of socially vulnerable
patients.»
«These results represent a significant advance in our understanding
of how commensal microbes can regulate host intestinal immune responses and suggest that the
identification of downstream targets in macrophages and dendritic cells along the GM - CSF axis can help the rationale design
of novel strategies for the treatment
of IBD
patients with defective GM - CSF function,» explained Dr. Merad.
«Currently, most victims
of elder abuse and neglect pass through our emergency departments with a life - threatening condition unidentified,» said the latter paper's lead study author, Tony Rosen, MD, MPH,
of Weill Cornell Medical College in New York, N.Y. «A multi-disciplinary, team - based approach supported by additional research and funding has the potential to improve the
identification of elder abuse and improve the health and safety
of our most vulnerable
patients.»
The earlier discovery
of mutations in UBQLN2 gene, which causes ALS and ALS / dementia in children and adults, in the Siddique lab led to the screening
of the UBQLN family
of genes in a large cohort
of patients with familial ALS, resulting in the
identification of the UBQLN4 mutation.
The authors
of the current study hypothesize that these previous trials may have inadvertently selected subjects who would be nonresponsive to the medication and conclude that future efficacy trials may require the
identification of subgroups
of patient populations.
«As treatments for the earliest stages
of AMD are developed in the coming years, correct
identification of AMD in primary eye care will be critical for routing
patients to treatment as soon as possible so that the disease can be treated in its earliest phases and central vision loss avoided.»
As a precaution, after
identification of fever, the healthcare worker was isolated and CDC staff interviewed the
patient to determine additional contacts or potential exposures.
In particular, the comparison
of gene sequences in large numbers
of patients and controls will be a key step in strategies for disease gene
identification.