They identified ALK - positive mesotheliomas by immunohistochemistry; confirmed with fluorescence in situ hybridization; and performed targeted next - generation sequencing of tumor DNA and RNA to get a full picture of the exact genetic rearrangement underpinning the disease.
Not exact matches
The NIH and Mass General are at the vanguard of a major effort to
identify and treat cancer based on causative gene mutations like the one found in
ALK.
Our primary aim is to
identify subgroups of rNB patients who have potentially targetable genetic (
ALK, MAPK pathway, Metabolic - related genes) and / or immunologic (tumor - associated macrophage infiltration and / or programmed death ligand [PD - L1] expression) biomarkers in rNB.