Sentences with phrase «identified as oncogenes»
In breast cancer, miR - 21, 155, 27, 96, 182, and 128 were identified as oncogenes, whereas miR - 125, 205, 27, 17, 206, and 145 were found to be tumor suppressor genes, and their corresponding target genes were also defined (10 — 12).
http://cancerres.aacrjournals.org/ Not exact matches
«Our study identified miR - 182 as a glioblastoma tumor suppressor that reduces the expression of several oncogenes that promote cancer development,» said senior author of the study Alexander Stegh, an assistant professor in the Ken and Ruth Davee department of neurology and of medicine at Northwestern University Feinberg School of Medicine.
In this study, researchers identified one microRNA (MIR548K) encoded in this region, and found it was characterized as a novel oncogene and functional assays which demonstrated that MIR548K enhances malignant phenotypes of ESCC cells.
Recent active research in miRNA identified a series of this type of molecules that are involved in tumor progression in various tumors as oncogenes and tumor suppressors (8, 9).
The oncogene was coupled with a fluorescent marker so that cells in which the oncogene was active could be easily identified, and as these cells proliferate, their «daughter» cells could also be tracked.
This often identifies thousands of potential targets and sometimes misses important ones like the oncogene RAS as a target of let - 7.