Not exact matches
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and
government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other
government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to
changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks
identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Such risks and uncertainties include, but are not limited to: our ability to achieve our financial, strategic and operational plans or initiatives; our ability to predict and manage medical costs and price effectively and develop and maintain good relationships with physicians, hospitals and other health care providers; the impact of modifications to our operations and processes; our ability to
identify potential strategic acquisitions or transactions and realize the expected benefits of such transactions, including with respect to the Merger; the substantial level of
government regulation over our business and the potential effects of new laws or regulations or
changes in existing laws or regulations; the outcome of litigation, regulatory audits, investigations, actions and / or guaranty fund assessments; uncertainties surrounding participation in
government - sponsored programs such as Medicare; the effectiveness and security of our information technology and other business systems; unfavorable industry, economic or political conditions, including foreign currency movements; acts of war, terrorism, natural disasters or pandemics; our ability to obtain shareholder or regulatory approvals required for the Merger or the requirement to accept conditions that could reduce the anticipated benefits of the Merger as a condition to obtaining regulatory approvals; a longer time than anticipated to consummate the proposed Merger; problems regarding the successful integration of the businesses of Express Scripts and Cigna; unexpected costs regarding the proposed Merger; diversion of management's attention from ongoing business operations and opportunities during the pendency of the Merger; potential litigation associated with the proposed Merger; the ability to retain key personnel; the availability of financing, including relating to the proposed Merger; effects on the businesses as a result of uncertainty surrounding the proposed Merger; as well as more specific risks and uncertainties discussed in our most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.cigna.com as well as on Express Scripts» most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.express-scripts.com.
At the very least the proposed
changes in Greater Manchester — which obviously go a lot wider than the system of
government — have all the hall marks of a policy being made on - the - hoof, behind closed doors, by small groups of like - minded people — just the sort of ingredients
identified by King and Crewe which lead to monumental blunders.
The UK Climate
Change Risk Assessment 2017 evidence report, prepared for the UK Government by the the Committee on Climate Change, identifies where more effort is necessary, and urgent, to address the risks of climate c
Change Risk Assessment 2017 evidence report, prepared for the UK
Government by the the Committee on Climate
Change, identifies where more effort is necessary, and urgent, to address the risks of climate c
Change,
identifies where more effort is necessary, and urgent, to address the risks of climate
changechange.
However, by ruling out
changes to the rates of National Insurance Contributions (NICs) in relation to employment and self - employment, the
Government are denying themselves many of the tools they need to tackle the issues Taylor
identified around employment status.
FSB members have already
identified cutting payroll taxes as the most important
change the
Government could make to encourage them to take on another member of staff.
Diabetes UK is working for a future without diabetes and we call on the
government to work with us in prioritising diabetes research that will lead to the prevention of Type 2 diabetes and long term behaviour
change and join us in supporting the long term vision of
identifying cures for both Type 1 and Type 2 diabetes.
Once we have considered the responses we receive, we will report to the relevant
Governments in the UK setting out any recommendations for
change that we have
identified which fall within their remit.
A prosecution witness, Mr Williams Obiara, an operative of DSS, who testified behind a veil, was requested by the prosecution counsel, Oladipupo Okpeseyi SAN, to
identify and display in the open court the weapons allegedly found in Dasuki's house in 2015, four days after the
change of
government.
Okanlawon, while congratulating the Federal
Government for looking in the direction of Sukuk as an alternative revenue source for infrastructure provision, said Nigerians have reasons to give kudos to Aregbesola for his ability to
identify and raise the awareness on Sukuk as an easier avenue of raising funds for live -
changing projects.
On receipt of our letter, the Cabinet Secretary investigated the circumstances,
identified a breach of Civil Service rules and forced the Labour Party to substantially
change its website: «references there have now been amended to make clear [Backing Young Britain] is a
government initiative»:
The goal of the new rule is to help local
governments identify vulnerable areas affected by climate
change that they can show to federal and state officials as a way to obtain money for things like road rebuilding.
The Australian
government recently invested nearly $ 500 million in climate
change research, including $ 126 million specifically earmarked to
identify the best strategies for adaptation to hotter days, storm surges, drought, and rising sea levels.
The
Government's Innovation Statement
identifies important elements of this ecosystem: from tax incentives to educational initiatives to
changes to insolvency laws.
Keeping in mind that each branch of
government has a distinct and separate role, it is appropriate for Governor Haslam to
identify changing priorities.
Canadian Fixed Income is a site I visit frequently after the markets close to
identify changes in the fixed income market for Canadian bonds (
government, corporate, municipals and real return)
Changing government regulations, newly
identified toxins, newly reported claims, new theories of liability, new contract interpretations and other factors could result in significant increases in these liabilities.
Most authors
identify government practices as being far more influential drivers than climate variability, noting also that similar
changes in climate did not stimulate conflicts of the same magnitude in neighboring regions, and that in the past people in Darfur were able to cope with climate variability in ways that avoided large scale violence.
This policy brief looks at how five county
governments in Kenya have established County Climate
Change Funds (CCCFs) that
identify, prioritize and finance investments to reduce climate risk and achieve adaptation priorities.
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Identify Adaptive Measures
Then, it was in Warsaw when the Venezuelan
government announced that they would host the preCOP, a Venezuelan
government which bears as an insignia the communist legacy of Hugo Chavez, and is
identified within the UNFCCC (Climate
Change Conference of the UN) as a country with sharp criticism of the lack of ambition by many other nations in regard to dealing with climate c
Change Conference of the UN) as a country with sharp criticism of the lack of ambition by many other nations in regard to dealing with climate
changechange.
The federal auditors found that the federal
government has not undertaken strategic
government - wide planning to manage climate risks by using information on the potential economic effects of climate
change to
identify significant risks and craft appropriate federal responses.
As a part of its efforts to reduce the impacts of climate
change the
government of Kenya has
identified the need to develop a comprehensive national carbon accounting system for Kenya (NCAS - K).
Along with opinion surveys, focus groups and other discussion forums, the
government can
identify changes to expenditure that are widely supported.
The IPCC was established by the World Meteorological Organization (WMO) and the United Nations Environment Program (UNEP) in 1988 to assess for
governments the scientific, technical and socio - economic information relevant for the understanding of climate
change, and to
identify its potential impacts and options for adaptation and mitigation.
Last year, the German
Government's Advisory Council on Global
Change released a report titled Climate
Change as a Security Risk which
identifies six threats to international stability and security from global warming.
The Lowy Institute report argues that expected climate
change «poses fundamental questions of human security, survival and the stability of nation states» and
identifies food shortages, extreme weather events and rising sea - levels as potential causes of large - scale, unregulated population movements in Asia and destabilisation of
governments unable to respond.
she
identifies some of the principals in the spreading of what she calls this «alarmist rhetoric» to be various United Nations agencies, NGOs, national
governments, security pundits, the popular media and — quite specifically — the Norwegian Nobel Committee of 2007, which, as she describes it, «warned that climate - induced migration and resource scarcity could cause violent conflict and war within and between states when it awarded the Nobel Peace Prize to Al Gore, Jr. and the Intergovernmental Panel on Climate
Change.»
Maplecroft's head of environment, James Allan, said that
identifying where the risks of climate
change were going to be highest was «now an imperative for both business and
governments.»
I think we all know that the
governments of the industrialized countries aren't going to act or make painful
changes in any meaninful time frame, so to me the only meaningful direction we can take this is to try to
identify things that each of us as individuals can start to do or work toward, and to understand whether that grass roots level participation really has any hope of making a difference.
Having
identified natural disasters, industrial pollution, health and sanitation, deforestation, desertification,
changes in climatic condition, salinity and deteriorating habitat of flora and fauna as the main environmental problems (Ministry of Environment and Forest, 35), the
Government of Bangladesh (GOB) then had to
identify a plan of action to deal with these issues.
In 2015, the Ontario
government initiated the
Changing Workplaces Review (Review) with a view to
identifying potential reforms to the Employment Standards Act, 2000 (ESA) and the Labour Relations Act, 1995 (LRA) to ensure that the province's employment standards and labour relations laws continue to reflect modern realities.
The federal
government is proposing
changes to these provisions with the objective of addressing concerns that have been
identified: http://www.cic.gc.ca/english/department/acts-regulations/forward-regulatory-plan/new-sponsored-spouses.asp
We believe that such a
change, in addition to the
changes described in the paragraph above, responds to commenters» concern that the NPRM would have allowed creation of a
government data base of personal
identifying information.
Ontario
identified ways to take proactive steps to battle existing systemic racism and prevent it in future through
changes to
government programs, services and decision - making, including such
changes as those recently made to the judicial application process.
The TSRA, CSIRO and Queensland
government submissions to House of Representatives Standing Committee Inquiry into climate
change and environmental impacts on coastal communities both
identified a lack of data as an issue.
As a first step in
identifying climate
change opportunities and issues that may arise on the Indigenous estate, State
Governments will need to work with Indigenous groups to resolve outstanding tenure issues.
5.4 That
government departments which have specific responsibilities for Indigenous affairs (for example, FaHCSIA and Attorney - General's Department), work closely with departments responsible for climate
change policy to ensure that the social, cultural, environmental and economic impacts of climate
change on Indigenous peoples are
identified and addressed.
As
identified by the United Nations Permanent Forum on Indigenous Issues (UNPFII),
Governments must work together at all levels with the full participation of Indigenous people on a «holistic» response to climate
change that takes account of not only the ecological dimensions of climate
change, but also the social impacts and principles of human rights, equity and environmental justice.
He
identified as a challenge «closing the gap» between the expectations of
government and Aboriginal and Torres Strait Islander peoples in order to avoid the credibility problems of previous bodies, to ensure that it has influence with
government and is an effective agent of
change for communities.
(18) It
identifies counterveiling provisions such as, the provision for
governments and native title holders to agree to
change the effect of the validation provisions; the provisions which reinstate native title where the holders are in possession and the land is vacant crown land; and the provision of compensation where native title is affected by the validation of intermediate period acts.
I strongly urge the
Government, in keeping with its commitment to avoid
changes that have the effect of winding back native title, to give serious consideration to abandoning or amending the proposals
identified above as recommended.
Whether the
government's
changes to the claims resolution process will resolve the problems
identified by the CR Review will become clearer as the
changes take effect.
6.5 That
government departments that have specific responsibilities for Indigenous affairs (for example, the Department of Families, Housing, Community Services and Indigenous Affairs and the Attorney - General's Department) work closely with the Department of Environment, Water, Heritage and the Arts, and the Department of Climate
Change, to ensure that the social, cultural, environmental and economic impacts and opportunities for Indigenous peoples arising from water and climate change are identified and add
Change, to ensure that the social, cultural, environmental and economic impacts and opportunities for Indigenous peoples arising from water and climate
change are identified and add
change are
identified and addressed