Sentences with phrase «identified hematopoietic»

RhoH is a newly identified hematopoietic small G protein, originally cloned as one of the genes frequently disrupted in diffuse large B cell lymphoma (1, 2).

Not exact matches

Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified RNA - based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a particularly problematic disease that typically afflicts older patients who have often already experienced a bout with cancer.

Basic research has centered on identifying and characterizing hematopoietic stem cells, however, it is still not clear how hematopoietic stem cells actually work, and how they are regulated because of the complexity of the bone marrow microenvironment.

«We used different groups of mice, in which either the oestrogen receptor or RANKL was inactivated in hematopoietic cells or in mesenchymal cells, to be able to identify the target cells of the hormone.

There are no specific markers to identify them; however, they are negative for hematopoietic cell markers like CD34 / 45 / HLA - DR and express CD90 / 73/105 on their surface 2, 3, 4.

Urgent evaluation to help identify optimal hematopoietic stem cell donor for individuals with a hematologic disorder and a family history that raises concerns

As an extension to genetics projects, we now aim to identify and characterize in greater depth genes implicated in hematopoietic development in the EU FP7 - funded BLUEPRINT project, which will generate reference genomes and epigenomes of at least 100 specific blood cell types.

Bone marrow derived - hematopoietic stem cells (HSCs) were the first stem cells to be identified and to reach the clinic.

Title: Genetic Screen Identifies MicroRNA Cluster 99b / let -7 e / 125a as a Regulator of Primitive Hematopoietic Cells Authors: Gerrits A, Walasek MA, Olthof S, Weersing E, Ritsema M, Zwart E, van Os R, Bystrykh LV, de Haan G Date: 2012 Publication Details: Blood 2012 Jan 12; 119 (2): 377 - 387

Retinoic acid — induced gene G (RIG - G), a gene originally identified in all - trans retinoic acid — treated NB4 acute promyelocytic leukemia cells, is also induced by IFNα in various hematopoietic and solid tumor cells.

Activating mutations in tyrosine kinases have been identified in hematopoietic and nonhematopoietic malignancies.