American Humane Association's Animal Welfare Research Institute has
identified multiple diseases and disorders that afflict both animals and children, to include cancer, diabetes, respiratory syncytial virus, asthma, food borne illnesses, obesity, neurological disorders and tuberculosis.
«Innovative genetic, cellular techniques help
identify multiple disease targets: CRISPR - Cas9 and iPSC advances hold treatment promise for schizophrenia, addiction, Zika infection and other diseases.»
Not exact matches
Through talking to experts in the field over the past year, Gates said he had
identified five areas of need: Understanding better how Alzheimer's unfolds, detecting and diagnosing it earlier, pursuing
multiple approaches to trying to halt the
disease, making it easier for people to take part in clinical trials of potential new medicines, and using data better.
Multiple genetic markers have been
identified for celiac
disease, but many genetically susceptible individuals tolerate gluten and never develop symptoms, leading to speculation about other risk factors, including early childhood nutrition.
Jaenisch says that the method that
identified the single point mutation in SNCA's enhancer could be used to pinpoint additional pathogenic genes for sporadic PD and sift through the GWAS hits for other
diseases, including Alzheimer's
disease, cancer, diabetes, and
multiple sclerosis.
The team
identified 345 regions of the genome where they could pinpoint the likely molecular causes underlying a person's predisposition to immune - related
diseases such as inflammatory bowel
disease, type 1 diabetes and
multiple sclerosis.
«The compounds
identified in this study, when administered orally, both reduced the inflammation that is a hallmark of
multiple sclerosis and protected against the nerve cell damage seen in mouse models of the
disease,» said Jeffery Haines, PhD, a post-doctoral fellow at Mount Sinai and the study's lead author.
«Once this has been achieved,» he explains, «we will be seeing a new era of pre-implantation genetic diagnosis aimed at,
identifying disease - free blastocysts,
identifying developmentally competent blastocysts among a cohort developing in vitro and achieving single blastocyst transfer in order to avoid
multiple births.»
«Research team first to
identify AF1q protein associated with
multiple myeloma, extramedullary
disease.»
«We wanted to
identify some potential therapeutic targets that are common not just to one but to
multiple forms of retinitis pigmentosa at late - stage
disease, when it is more likely to be clinically diagnosed in a patient population.»
Researchers in the Jacobs School of Medicine and Biomedical Sciences at UB are continuing to study cerebral microbleeds,
identified in the image above, as indicators of
disease progression in
multiple sclerosis.
«Our discovery proposes a new and alternative way to conduct research into
multiple sclerosis, by, for the first time,
identifying a clear link to other neurodegenerative
diseases.
Identifying these factors is relevant for further understanding Parkinson's
disease and
multiple system atrophy,» adds Elias Bechara, CRG researcher and one of the authors of the article.
Because
disease organisms mutate quickly to overcome crop resistance controlled by single genes, researchers are rushing to
identify new resistance genes and to incorporate
multiple genes into high - yielding varieties, according to Ravi Singh, CIMMYT wheat scientist who participated in the reported study.
A UC San Francisco - led research team has
identified the likely genetic mechanism that causes some patients with
multiple sclerosis (MS) to progress more quickly than others to a debilitating stage of the
disease.
One of its priorities is to develop relevant strategies to decipher
multiple forms of neuromuscular
diseases,
identify new therapeutic targets and foster novel strategies for innovative treatments.
«We are currently working to
identify the relationship between the circadian clock, metabolism and the immune system, so that one day we could develop therapies to treat
diseases influenced by circadian clock disruption — including not only obesity and diabetes, but also potentially
multiple sclerosis and even Alzheimer's
disease.»
Our scientists have also pointed the way to a new therapeutic strategy for
multiple sclerosis and other neurological
diseases by
identifying that a blood protein, fibrinogen, plays a causal role in damaging the central nervous system.
Whole - exome sequencing has
identified the causes of several Mendelian
diseases by analyzing
multiple unrelated cases, but it is more challenging to resolve the cause of extremely rare and suspected Mendelian
diseases from individual families.
A novel GWAS has
identified multiple genomic links between clinical laboratory measurements and several complex
diseases in a Japanese population.
«Our research on the role of blood proteins in brain functions has
identified new targets for therapeutic intervention in
multiple sclerosis and other neurological
diseases,» said Dr. Akassoglou.
Performing genetic studies in
multiple human populations can
identify disease risk alleles that are common in one population but rare in others, with the potential to illuminate pathophysiology, health disparities, and the population genetic origins of
disease alleles.
Identifying a reliable biomarker may accelerate diagnosis of
multiple sclerosis (MS) and lead to early management of the
disease.
As with most technologic methods, we expect
multiple replicate analyses of the highly fractionated samples would result in a reduction of the number of seemingly unique proteins
identified for each
disease group [33].
In instances of one of the more common autoimmune
diseases,
multiple sclerosis, or MS, this means
identifying potential triggers and working with individuals to develop a lifestyle that is conducive to avoiding the worsening of symptomology.
The goal was to determine the ability of
multiple biomarkers to
identify and assess, and hopefully correlate to, the degree of heart
disease in cats.
There are
multiple causes of kidney
disease and one of the very frustrating things about this
disease is that often by the time it is
identified, the cause itself is no longer present and is no longer treatable.
With this panel, we can
identify, or rule out,
multiple diseases inherited in Labradors, such as hip dysplasia, ruptured anterior (cranial) cruciate ligament, mast cell tumor, T and B - cell lymphoma, posterior polar cataracts, liver
disease, laryngeal paralysis, degenerative myelopathy, epilepsy, tricuspid valve dysplasia and obesity.