Conclusions: We thus developed an FGF2 - induced model of human β - cell dedifferentiation,
identified new markers of dedifferentiation, and found evidence for increased pancreatic FGF2, FGFR1, and β - cell dedifferentiation in T2D.
Similar experiments could
identify new markers of diseased tissue or new targets for targeted molecular therapies.
By comparing RNA sequencing with the Human Protein Atlas, we've also been able to
identify new markers for the bile ducts that confirm the malformations that develop in patients with Alagille Syndrome.»
Gerrit Jan Schuurhuis of the Free University Medical Center in Amsterdam and his colleagues recently
identified the new marker, called C - type lectin - like molecule - 1 or CLL - 1, in 92 percent of people with a form of acute myeloid leukemia.
Not exact matches
MMRF and Memorial Sloan Kettering to launch a
new clinical trial to
identify potential genomic
markers linked to achieving and maintaining deep response to therapy Read More
The
new research has the potential to be used by the bakery sector to allow for more accurate testing for the presence of these
marker proteins, thereby
identifying so - called «hidden allergens».
Such clear differences in biomarker signatures are an important step in
identifying new disease
markers, and perhaps therapeutic targets.
Through a
new study of the coccobacillus Francisella, Los Alamos National Laboratory researchers are working to use DNA
markers to discern related but relatively harmless species as they are
identified and to provide a means to distinguish them from the harmful F. tularensis.
Despite this, the extensive breadth of the
new study allowed the researchers to
identify several genetic
markers underlying the fruit size increases, which is great news for breeders who might want to further increase the apple's girth.
Researchers at Stanford University School of Medicine have
identified several
new biological
markers to measure the progression of the inherited neurodegenerative disorder Huntington's disease (HD).
«These lung breakdown products have never been
identified in TB before, and have the potential to be used as
new markers to
identify patients with TB and monitor the effect of
new treatments on lung damage.
The goal is to
identify new disease diagnostic
markers and develop
new therapies, according to the company's head of R&D in China, Andreas Tschirky, and chief scientific officer Li Chen.
The
new method for replicating genetic
markers, SNPs via MPS, were found to be successful in
identifying the ancestry of a suspect in most tests in the laboratory, which can provide another avenue for testing degraded DNA samples.
«This opens a
new door in
identifying biological
markers for dementia since we might consider using the brain's processing of speech sounds as a
new way to detect the disease earlier,» says Dr. Claude Alain, the study's senior author and senior scientist at Baycrest's Rotman Research Institute (RRI) and professor at the University of Toronto's psychology department.
Published in The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, the
new study found that older patients with delirium had significantly elevated levels of the inflammatory
marker interleukin - 6 (IL - 6) two days after surgery and also
identified elevated levels of interleukin 2 (IL - 2) in delirious patients.
Using these data, researchers
identified four
new markers of primary sclerosing cholangitis risk on the human genome, bringing the total number of known predisposing locations to 20.
«
New cancer
marker identified; possible therapeutic target for breast cancer.»
A
new study indicates that, at least for most major groups in the United States, self -
identified ethnicity corresponds closely with what genetic
markers reveal, suggesting that race can be a useful guide to at least some aspects of biology.
In an effort to
identify a biological
marker to help guide intervention, a
new study in Biological Psychiatry reports that postoperative delirium is associated with signs of inflammation — specifically elevations in the inflammatory
marker C - reactive protein (CRP)-- in patients 70 years of age or older.
Another student who was using phage - display technology to
identify new molecular
markers in ovarian cancer attended a clinic in gynecologic oncology once a week throughout her dissertation research.
For instance, company researchers have recently
identified a promising
new genetic
marker for a particular cancer; because Avalon already has all the patents filed on the discovery, Carter and the management team recently gave the scientists the go - ahead to write up two papers on the work.
This is why our system is innovative and powerful, as we don't have to spend the time to
identify and develop a
new genetic or protein
marker for every kind of cancer.»
According to a
new «proof of principle» study published in Aug. 27 issue of Cancer Prevention Research, Moffitt Cancer Center researchers hope to improve pancreatic cancer survival rates by
identifying markers in the blood that can pinpoint patients with premalignant pancreatic lesions called intraductal papillary mucinous neoplasms (IPMNs).
Researchers have
identified two
new biological
markers of cystic fibrosis (CF), a genetic disease which affects children and young adults, leaving them with lifelong health complications including digestive problems and persistent lung infections.
These results, if validated by other research groups, could provide a
new marker for
identifying DCIS that are more likely progress to invasive disease, however more importantly may highlight a group of DCIS patients where no treatment is necessary.
(HealthDay)-- A protein «biomarker» in bile correctly
identifies pancreatic cancer and may detect the cancer earlier than some
markers in blood, according to a
new study.
In addition to
identifying new genes, researchers hope to find genetic
markers that might influence how a known genetic syndrome presents within a particular family.
A
new marker that could be used to diagnose fatal breast cancer up to one year ahead of current methods has been
identified in...
Researchers have
identified seven genetic
markers linked with a woman's breast size, according to a
new study.
Howard Hughes Medical Institute researchers have
identified a
new biological
marker present in the urine of patients with prostate cancer that indicates whether the cancer is progressing and...
Howard Hughes Medical Institute researchers have
identified a
new biological
marker present in the urine of patients with prostate cancer that indicates whether the cancer is progressing and spreading.
Six Xa genes have been tagged with molecular
markers and used to help
identify new resistant lines, resulting in the release of resistant varieties in several countries.
Dr. Lanteri is also interested in using the OMICS approach to
identify predictive
markers of disease outcome and
new therapeutic targets.
New computational strategies are supported by our single cell data analysis experts with computational methods deconvolute tissue composition, determine cell type heterogeneity,
identify novel cell type defining
markers or track transcriptional dynamics.
In recent years, many labs have dedicated enormous resources to
identifying new molecular cancer
markers through «unbiased» direct profiling of human cancers using DNA microarray approaches.
Mammary progenitors
identified by a
new marker, ICAM - 1, undergo epithelial - mesenchymal transition and luminal - to - basal switch in response to paracrine Met activation.
Speaking of those cue
markers, I'm at a loss to
identify the source of this
new transfer.
Smart trailer tow module, using an all -
new smart trailer tow wiring harness that helps
identify and inform the driver of potential trailer connectivity issues, burned or unlit trailer
marker lamps, and brake light and trailer battery faults.
• Accept handmade sketches of buildings and convert them into 3D and 2D CAD master pieces as per instruction and preferences of the clients • Utilize AutoCAD and other CAD software for drafting various legal land agreement plans as instructed • Locate and
identify the existing map data to support
new building plans • Produce colorful copies of landscape plans using CAD
markers