Sentences with phrase «identified nonsynonymous»

Instead, the authors identified nonsynonymous coding variants in met WGS data, and validated them by PCR / 3730 sequencing in the met, tumor, and normal samples.

Not exact matches

First, we used branch tests as implemented in PAML to identify genes where the fixation rate of nonsynonymous mutations was significantly faster than the fixation rate of synonymous mutations in the domesticated horses (FDR = 5 %).

Results.: For the nonsynonymous SNPs other than the ADAMTS10 variant, control dogs were identified that were homozygous for the alternative alleles, ruling out those variants as causative.