Sentences with phrase «identified ortholog»
In a 2016 National Institutes of Health summer internship at the National Human Genomic Research Institute, Sappington conducted a third research project in which she demonstrated a fast, alignment - free computational method for identifying orthologs — similar genes from species that are related by descent from a common ancestor.
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We were able to identify 3,771 ortholog pairs by sequence similarity and investigated the ortholog pair alignment length.
As expected, an ortholog of AtDwf4 and OsDwf4 in S. viridis (SvDwf4; Sevir.9 G483600) was identified.
In addition, one of the genes identified — an ortholog of human COL2A1 is commonly used as a chondrocytic maker in the development of cartilage (Zaucke et al., 2001).
Among the genes that were identified to be up - regulated are orthologs that encode for human collagen proteins: ADAMTS2, ADAMTS7 and COL2A1.
Whereas 12 of 16 annotations were confirmed by RT - PCR in human tissues, for only seven genes mouse orthologs could be identified and found to be expressed.
Benchmarking Universal Single - Copy Orthologs (BUSCO) analysis showed that the pipeline was able to identify at least 95 % of BUSCO.s plantae dataset.
One to one BLAST orthologs were identified by reciprocal BLASTP searches between D. plexippus and the B. mori OGS peptides (downloaded from SilkDB http://silkworm.genomics.org.cn/silkdb).