Sentences with phrase «identified phosphatases»

Not exact matches

Page and his colleagues, who use animal models to understand how autism risk factors impact the developing brain and to identify potential treatments for the condition, have found that animals with mutations in the autism risk gene phosphatase and tensin homolog (Pten) mimic aspects of autism, including increased brain size, social deficits and increased repetitive behavior.

By searching for gene deletion patterns in cancer through a concept the investigators call «synthetic essentiality,» the team identified a synthetic essential gene known as chromatin helicase DNA - binding factor (CHD1) as a therapeutic target for prostate and breast cancers lacking a tumor suppressor gene called phosphatase and tensin homolog (PTEN).

Igaki identified the ligand Sas and the receptor - type tyrosine phosphatase PTP10D as the cell - surface ligand - receptor system that drives tumor - suppressive cell competition.

Through a genetic screen in Drosophila, Igaki identified the ligand Sas and the receptor - type tyrosine phosphatase PTP10D as the cell - surface ligand - receptor system that drives tumor - suppressive cell competition.