The advancement could one day lead to a new generation of medical sensors that are able to
identify abnormal cells.
Not exact matches
Researchers from UC Davis School of Medicine and Shriners Hospitals for Children — Northern California have
identified a group of
cells in the brain that they say plays an important role in the
abnormal neuron development in Down syndrome.
A study led by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James) has
identified an
abnormal metabolic pathway that drives cancer -
cell growth in a particular glioblastoma subtype.
Once the team derived the stem
cells, they
identified a cellular mechanism that drives
abnormal bone growth in the thus - far untreatable bone disease, called fibrodysplasiaossificans progressiva (FOP).
Using sensitive genetic sequencing technology, the scientists
identified unique RNA splicing variants that distinguish normal, aging stem
cells from
abnormal, malignant ones.
A key challenge of treating these cancers has been to
identify a way of eliminating the
abnormal T -
cells whilst sparing the healthy ones that play an essential role in providing protection against infections.
«Analysis of metastatic prostate cancers suggests treatment options: Study maps out
abnormal signaling pathways in prostate cancer
cells and provides computational approaches to
identify individualized targets for therapy.»
A new biomarker could help
identify abnormal breast
cells that will develop into tumours, according to research published in Clinical Cncer Research.
Thomas Look and colleagues use a type of genomic screen and
identify abnormal HGF expression as a crucial factor for development of a class of acute leukemia in leukemia
cell lines and clinical samples.
Antibody dependant cellular cytotoxicity (ADCC)- When antibodies coat an HIV - infected
cell identifying it as something
abnormal that needs to be killed.
Key findings of this research, which was conducted by Shawn L. Chavez, PhD and her colleagues at Stanford University and analyzed at OHSU, showed that by looking at the duration of the first mitotic phase — a short period in the
cell cycle — one can
identify chromosomally normal versus
abnormal embryos up to approximately the 8 -
cell stage.
Luckily, different
cell types tend to have different things on their surfaces, which play particular parts in their specialized roles in the tissue, so it is a matter of
identifying and targeting
cell - surface markers that are specific to these
abnormal cell types.
To achieve this goal, the center's clinical and basic investigators are engaging in four distinct yet synergistic projects: 1)
identifying mechanisms of
abnormal cell proliferation, 2) examining the role of thrombosis in the development of PAH, 3) studying the role of nitric oxide deficiency in PAH, and 4) testing two existing drugs to restore lost cellular function due to a genetic mutation related to PAH.
While imaging captures brain activation during specific tasks and therefore may
identify general brain regions that are
abnormal in diseases, it does not have that critical
cell - level resolution.
It supports macrophages and helper T -
cells to
identify and destroy
abnormal cells and dangerous microbes.
A complete blood count (CBC) delivers valuable information to
identify anemia, infection, blood - borne parasites and
abnormal blood
cells.
For more challenging cytologies, especially cancer
cells that are very
abnormal, samples will be sent off to a pathologist who specializes in
identifying these kinds of
cells and has access to special stains.
The CBC provides details about the number, size and shape of the various
cells types, and
identifies the presence of
abnormal cells in circulation.
Treatment is to
identify and treat underlying disease process; such as sex hormone related adrenal hyperplasia (
abnormal cell growth) which is treated with lysodren.
A CBC (complete blood count) delivers information to
identify anemia, infection,
abnormal blood
cells, and blood - borne parasites.
A full workup of a complete blood
cell count, a biochemical profile, fecal examination, and radiographs (x-rays) is recommended to help
identify or rule out an underlying medical condition.1, 2 Depending on the presenting signs of the bird, other tests can be run to check for infectious organisms, skin parasites, or
abnormal hormone levels.
The reason this process goes un-noticed and is inconsequential the overwhelming majority of the time, is because our immune systems are up to the task of
identifying and clearing the
abnormal cells before they have a chance to gain an established presence and / or spread in our bodies.