«develop a well - defined reference, or «baseline,» of good health as well as a rich data platform that may be used to better understand the transition from health to disease and
identify additional risk factors for disease»
Gerard Schellenberg, Ph.D., University of Pennsylvania School of Medicine in Philadelphia, leads the consortium, which aims to
identify the additional risk factor genes for late - onset AD.
Not exact matches
While it has yet to make the official list, some studies have
identified VOCs and
additional indoor air pollutants as a
risk factor for SIDS.
A study by investigators at Brigham and Women's Hospital (BWH) published this week in PLOS ONE
identifies four
factors that may account for sex differences in statin therapy among patients with coronary artery disease (CAD), pointing to interventions and
additional research that will be needed to help overcome this sex disparity and reduce cardiovascular
risk for women.
«Right now, we recommend testing for the HLA - B * 5801 variant among those patients, and further research may help to
identify additional factors that can improve
risk management.
«Once
additional key clinical and genetic
factors are
identified, infants who are determined to have a low
risk of requiring medication can be sent home without prolonged monitoring, and those who are predicted to have a difficult clinical course can be started on more aggressive treatment earlier, which will lead to shorter hospitalizations and improved outcomes.»
The United Kingdom - based group, led by Julie Williams, Ph.D., Cardiff University School of Medicine, Wales, found the same genes as
risk factors and
identified a gene variant ABCA7 as an
additional gene of interest.
These
risks and uncertainties include, among others, those relating to our ability to obtain financing and to form collaborative relationships, uncertainty regarding potential future deterioration in the market for auction rate securities which could result in
additional permanent impairment charges, our ability to develop and market diagnostic products, the level of third party reimbursement for our products,
risks related to preclinical and clinical development of pharmaceutical products, including the identification of compounds and the completion of clinical trials, the effect of government regulation and the regulatory approval processes, market acceptance, our ability to obtain and protect intellectual property rights for our products, dependence on collaborative relationships, the effect of competitive products, industry trends and other
risks identified in deCODE's filings with the Securities and Exchange Commission, including, without limitation, the
risk factors identified in our most recent Annual Report on Form 10 - K and any updates to those
risk factors filed from time to time in our Quarterly Reports on Form 10 - Q or Current Reports on Form 8 - K.
This genetic
risk factor is independent of other
risk factors, such as cholesterol, obesity and smoking, and therefore provides an
additional method for
identifying individuals who may derive benefit from earlier and more aggressive prevention efforts.
15 In fact, type 2 diabetes (T2D)-- a condition stemming from broken glucose metabolism and insulin signaling — has been
identified as an
additional risk factor for developing AD.16, 17 Moreover, the pathological changes that occur in AD in the brain physically resemble those seen in the pancreas and vasculature in T2D.9, 18 Type 2 diabetics who carry ApoE4 alleles are at the greatest
risk for AD, with an even more severe
risk reserved for those treated with exogenous insulin.19 This suggests that either T2D or related features of the metabolic syndrome bring about AD, or that they are separate consequences of the same underlying cause — and moreover, that insulin is a key
factor.
Fama and French later expanded their model to include fixed income,
identifying term and default as two
additional risk factors that explain returns for fixed income.
For corporate bonds, we consider environmental, social, and governance (ESG)
factors to help
identify additional risk.
·
Identify children and families that may require
additional support to enhance their protective
factors and reduce their
risk for mental health difficulties.
Additional risk factors for poor father - child relationships
identified during the pre-school and school - age years include: adverse family events; weak home organisation; a less supportive family ethos and low levels of positive parenting.