Sentences with phrase «identify cancer drivers»

«Identifying a cancer driver is crucial for cancer treatment because it allows the use of targeted therapies, which have less side - effects than conventional chemotherapy drugs, against a particular protein,» said Kurokawa.

361/11: 00 Systematic analysis of mutation distribution in three dimensional protein structures identifies cancer driver genes.

Not exact matches

When tested on various cancer patient databases, iCAGES was found to be superior to other computational tools at predicting cancer drivers from personal genomes and at identifying beneficial treatment.

«Once identified, we further tested their role as cancer drivers, for example by looking at molecules with and without mutations and comparing their structure and function,» he adds.

In 2007, he joined Columbia University as a post-doc, where he developed network - based computational approaches aimed at identifying key drivers of initiation and progression of cancer, as well as mechanisms of therapeutic response and drug resistance.

As the first step in a next generation knowledge system for cancer, the GDC enables and accelerates efforts to identify both high - and low - frequency cancer driver mutations, assists in revealing the genetic determinants of response to therapy, and informs the composition of clinical trial cohorts.

University of Hawai'i Cancer Center researchers have identified an essential driver of tumor cell invasion in glioblastoma, the most aggressive form of brain cancer that can occur at anCancer Center researchers have identified an essential driver of tumor cell invasion in glioblastoma, the most aggressive form of brain cancer that can occur at ancancer that can occur at any age.

The group has used this approach to identify key drivers of metastatic cancer progression, and is leveraging this information to develop novel nanoparticles to block the spread of prostate and other cancers.

«Just 44 percent of the pediatric cancer driver mutations in this study matched those identified in adults,» said senior author Jinghui Zhang, PhD, St. Jude Computational Biology chair.

In particular, I have initiated a team approach that is identifying and studying recurrent, treatment - refractory cancers in our clinics using these approaches as a component of evidence - based diagnostic medicine, seeking to better understand the genomic drivers in these cancers and to identify novel treatment approaches that target them, in hopes of obtaining durable responses.

First Major Gene Mutation for Hereditary Prostate Cancer Found After a 20 - year quest to find a genetic driver for prostate cancer that strikes men at younger ages and runs in families, researchers have identified a rare, inherited mutation linked to a significantly higher risk of the diCancer Found After a 20 - year quest to find a genetic driver for prostate cancer that strikes men at younger ages and runs in families, researchers have identified a rare, inherited mutation linked to a significantly higher risk of the dicancer that strikes men at younger ages and runs in families, researchers have identified a rare, inherited mutation linked to a significantly higher risk of the disease.