Sentences with phrase «identify carriers of the disease»

As research advances, scientists hope to determine the precise location of a given gene so they can test entire populations to identify carriers of the disease gene.

Not exact matches

«We used different lines of evidence to show that ANGPTL3 deficiency is associated with a reduced risk of coronary artery disease,» said study co-author Kiran Musunuru, MD, PhD, MPH, an associate professor of Cardiovascular Medicine at Penn. «But ultimately we were able to identify that fact that carriers of this genetic mutation did in fact experience a benefit — with little other health risk.»

Individual screening tests can already identify silent carriers of many single faulty recessive genes — the kind that, when inherited in double (one copy from each parent), can lead to conditions such as cystic fibrosis and Tay - Sachs disease.

It is the first endangered species for which a test to identify carriers of a genetic disease has been established.

Heterozygous deficiency of APOC3 has been shown to protect against coronary heart disease; we identified APOC3 homozygous pLoF carriers in our cohort.

Consequently, despite the fact that it can not identify the «carrier» status, examination of tissues obtained by means of a liver biopsy still remains the method for positively diagnosing the disease, i.e. of identifying affected dogs.

While the diagnosis of retinal degeneration is made by ophthalmoscopy and / or electroretinography, genetic testing for PRA can be useful for breeders to identify not only affected animals, but those that are genetic carriers for the disease.

Both OptiGen and Paw Print Genetics offer inherited disease testing to identify carriers and affected dogs for a variety of different canine genetic conditions.

A diagnostic test of urine for elevated level of L -2-HGA can be used to identify dogs affected by the disease, but it does not allow for the detection of carriers.

Recently, it has become possible to identify presymptomatic dogs or carriers for a small number of inherited diseases in a few breeds using molecular genetic tests.

It is not always possible to prevent the occurrence of inherited diseases, as there are not yet definitive tests to identify carriers of genetic diseases.

With regard to breeding, it is important to identify genetic carriers of von Willebrand's disease.

Since carrier cats remain healthy though, and since affected cats may not necessarily be detected until they are a few years of age, the potential exists for both carrier and affected cats to have significant numbers of litters before the disease is identified.

Where possible, DNA tests are being developed for each disease so that breeders can identify carriers of conditions and make responsible decisions to help ensure that future generations are not affected.

The FWCC itself acknowledges the following: cats are the most common carriers of rabies among domestic animals, and can transmit rabies to wildlife such as raccoons, skunks an foxes; feline leukemia virus, a leading cause of death due to infectious disease in cats, has been reported in a mountain lion, a close relative of the endangered Florida panther; domestic cats were identified as one possible reservoir host for feline panleukopenia, which has been discovered in the Florida panther.