This allowed us to directly compare the patterns of marker expression in normal and induced retina, and
identify cell classes on the basis of their distinctive morphology and location within the eye.
Not exact matches
They
identified five receptors closely related to a
class of receptor already known to help immune
cells hone in on pathogens and inflammation.
A new study by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James) has
identified a mechanism by which cancer
cells develop resistance to a
class of drugs called fibroblast growth factor receptor (FGFR) inhibitors.
The approach enabled a wide range of studies of human brain development, including implicating a new
class of neural stem
cell recently discovered by the lab in the evolutionary expansion of the human brain and
identifying how the mosquito - borne Zika virus may contribute to microcephaly in infants infected in utero.
Thomas Look and colleagues use a type of genomic screen and
identify abnormal HGF expression as a crucial factor for development of a
class of acute leukemia in leukemia
cell lines and clinical samples.
Labeled
cell classes could also be
identified based on their morphology.
Example demonstrating how individual
cell classes were
identified based on morphology and
cell class - specific markers.
Timothy Springer, with colleagues Michael L. Dustin and Charles A. Dinarello,
identifies and characterizes adhesion molecules, a
class of
cell surface proteins that function in the interactions of immune
cells with other
cells, including antigen - specific recognition and
cell trafficking: integrin LFA - 1 involved in cytoskeleton and signaling, and intracellular adhesion molecules (ICAMs), which are binding partners (ligands) for LFA - 1 and are increased in inflammatory and autoimmune disease.
Retinal
cell classes were
identified based on their morphology, location within the retina, and using
cell class specific markers (Figures 5 and S2, S3, S4, S5, S6).
Ten years later, Ashworth
identified a way to exploit genetic weaknesses in cancer
cells that include mutated BRCA2, which led to the development of a successful new
class of cancer drugs known as PARP inhibitors.
Scientists devised a method to
identify different
classes of compounds with the potential for eliminating senescent
cells.
Instead, the researchers developed a high - throughput selection assay, CREATE (Cre REcombinase - based AAV Targeted Evolution), that allowed them to test millions of viruses in vivo simultaneously and to
identify those that were best at entering the brain and delivering genes to a specific
class of brain
cells known as astrocytes.
An excel spreadsheet that can be played with a
class as a quick recap to ensure they can
identify and use
cell references and understand that the letter (column) goes before the number (row).