Sentences with phrase «identify cells in tissues»

Because calcium imaging is widely used to identify cells in tissues throughout the body, researchers studying other systems will be able to benefit from the published methodology.

Not exact matches

The building block electronic and protonic actual occasions are, in the case of human beings, swept into vastly more complex, Chinese box - like sets of containing societies within which there are social levels that can be identified with cells, others which answer to Aristotle's levels of tissues and organs, and which finally are presided over by what Whitehead refers to as the regnant nexus, a social thread of complex temporal inheritance which, Whitehead suggests, wanders from part to part of the brain, is the seat of conscious direction of the organism as a whole, and answers to what in Plato and Aristotle is called the soul.

One of the key questions in biology is to identify how tissues are repaired after trauma and understand how stem cells migrate, proliferate, and differentiate to repair tissue damage.

These cells play a key role in autoimmune disease — in which the immune system mistakenly identifies the body's own tissues as foreign and attack them.

To address this gap in knowledge, Mirabello and Schiffman teamed up with co-senior author Robert Burk of Albert Einstein College of Medicine to sequence the whole genomes of 5,570 HPV16 - infected cell and tissue samples from women around the world and to identify associations between HPV16 genetic variants and the risk of cervical precancer and cancer.

Researchers are already using single - cell analysis to identify genetic variations within tumors and tissues, and Langsdorff says the technique is quickly establishing a foothold in microbiology as well.

They also applied it to human brain tissue collected by the Genotype - Tissue Expression (GTEx) Project, finding that they could a) identify expression signatures unique to neurons, glial cells, and other cell types in the brain (including rare types), and b) differentiate between closely related cell subtissue collected by the Genotype - Tissue Expression (GTEx) Project, finding that they could a) identify expression signatures unique to neurons, glial cells, and other cell types in the brain (including rare types), and b) differentiate between closely related cell subTissue Expression (GTEx) Project, finding that they could a) identify expression signatures unique to neurons, glial cells, and other cell types in the brain (including rare types), and b) differentiate between closely related cell subtypes.

Yin's research has identified the role of a microRNA, miR - 101a, a central genetic regulator, in stimulating both the growth of heart muscle cells and in removing scar tissue.

2006 Shinya Yamanaka identifies and activates a small number of mouse genes in the cells of connective tissue, showing they can be reprogrammed to behave like immature stem cells.

What's more, they identified Cas as a critical, tissue - specific target of Hh signaling, which not only plays a key role in maintaining follicle stem cells but also assists in the diversification of their progeny.

Investigators at the Cedars - Sinai Heart Institute — whose previous research showed that cardiac stem cell therapy reduces scarring and regenerates healthy tissue after a heart attack in humans — have identified components of those stem cells responsible for the beneficial effects.

Split Pool Ligation - based Transcriptome sequencing (SPLiT - seq) is a scalable technique for characterizing RNA in individual cells that can be used to identify the various cell types found in the brain and other tissues.

By manipulating it in vitro, a team of researchers led by Prof. David Mooney at Harvard SEAS have identified a possible mechanism by which normal cells turn malignant in mammary epithelial tissues, the tissues frequently involved in breast cancer.

«Our study has identified Paneth cells as initial virus sensors in the gut that may induce early gut inflammation, cause tissue damage and help spread the viral infection.

He is trying to identify the molecules with which the klotho protein interacts in tissues and to figure out how cells with defective klotho behave differently from normal cells.

Chemists in California have identified and synthesised a complex sugar molecule which lies on the surface of white blood cells, and through which the cells «recognise» those blood vessels that lie near injured tissue.

Easily accessible from nasal biopsies, these cells — which belong to nerve tissues and can differentiate into neurons — constitute an interesting model to identify the genes and proteins whose expression is deregulated in patients with ASD.

But locating the cells that contain the 50 - nanometer particles has been like looking for a needle in a haystack, in part because the tissue - dissolving methods used to identify magnetite turn biological samples to mush.

If the compound identified in this study successfully reduces tissue death and improves recovery in further experiments, it could lead to new approaches for preserving brain cells after an ischemic stroke,» said Francesca Bosetti, Ph.D., Pharm.D., program director at the NIH's National Institute of Neurological Disorders and Stroke (NINDS).

Researchers at Oregon State University have developed a new way to selectively insert compounds into cancer cells — a system that will help surgeons identify malignant tissues and then, in combination with phototherapy, kill any remaining cancer cells after a tumor is removed.

Once in place, and exposed to the type of light needed, the cancer cells then will glow — creating a biological road map for a surgeon to follow in identifying what tissues to remove and what to leave.

Together these data suggest that the F4 / 80 + cells identified in adipose tissue are CSF - 1 — dependent, bone marrow — derived adipose tissue macrophages.

Furthermore, they integrated single - cell datasets of pancreatic tissue from humans and mice, thereby identifying 10 cell types that were shared across species and defining the evolutionary changes occurring in each group.

Again they sequenced the viruses they found in the various mosquito tissues, and they identified two new mutants, both with mutations in the same lock - picking coat protein as the original Reunion mutant, results they published last year in Cell Host and Microbe.

In particular, the research identified several genes regulated by methylation in the egg that are involved in cell adhesion and migration — both vital properties for cells of the developing placenta in establishing connections with maternal tissues to support embryo developmenIn particular, the research identified several genes regulated by methylation in the egg that are involved in cell adhesion and migration — both vital properties for cells of the developing placenta in establishing connections with maternal tissues to support embryo developmenin the egg that are involved in cell adhesion and migration — both vital properties for cells of the developing placenta in establishing connections with maternal tissues to support embryo developmenin cell adhesion and migration — both vital properties for cells of the developing placenta in establishing connections with maternal tissues to support embryo developmenin establishing connections with maternal tissues to support embryo development.

The team will also be looking to identify which molecule L - selectin binds to in virus infected tissues that allows killer T cells to be directed there.

To identify the molecular mechanisms of neural stem cell plasticity in adult zebrafish brain after various types of tissue damage or physiological stimulations

An MDI Biological Laboratory assistant professor says he has identified processes that underlie how heart tissue regenerates, which in turn holds out hope of finding new drugs that can help the body grow muscle cells and get rid of scar tissue.

Cell Distance Mapping Identifies Functional T Follicular Helper Cells in Inflamed Human Renal Tissue.

Genetic approaches in mouse model systems combined with cell biological assays have allowed Professor Lukas Sommer to identify mechanisms regulating stem cell fates in the developing CNS and in neural crest - derived tissues.

This work builds on previous studies identifying the stem cell population in the nail bed by unveiling a signaling mechanism that could be exploited to enhance the amount of tissue that could be regrown.

This renewed interest in phagocytes provides an ideal starting point for a meeting of cell biologists, immunologists, and developmental biologists interested in further exploring the phagocyte's fundamental role in tissue biology, identifying gaps in our current knowledge, and defining disease pathways, beginning with infection and inflammation and extending beyond.

Luckily, different cell types tend to have different things on their surfaces, which play particular parts in their specialized roles in the tissue, so it is a matter of identifying and targeting cell - surface markers that are specific to these abnormal cell types.

In the next year, members of the Dream Team will continue to study the tumor microenvironment before and after checkpoint blockade, to develop algorithms to identify and predict the best antigens on cancer cells that can be used for cancer immunotherapies, to analyze tumor tissues and blood for biomarkers that will help in selecting patients who will benefit, and identifying the best approaches to increase the strength of immune cells for adoptive cell therapIn the next year, members of the Dream Team will continue to study the tumor microenvironment before and after checkpoint blockade, to develop algorithms to identify and predict the best antigens on cancer cells that can be used for cancer immunotherapies, to analyze tumor tissues and blood for biomarkers that will help in selecting patients who will benefit, and identifying the best approaches to increase the strength of immune cells for adoptive cell therapin selecting patients who will benefit, and identifying the best approaches to increase the strength of immune cells for adoptive cell therapy.

This symposium will cover cell and developmental biology, tissue biophysics, theoretical modelling, organoids and synthetic biology, and provide a platform to discuss and identify key approaches and future collaborations in tissue self - organisation.

March 6, 2018 — Researchers identified a type of stem cell that produces new air sac cells in lung tissue.

«We saw hundreds of changes in genes in cancer cells that had not been identified before, and for each of these, HHMI research associate Alberto Bardelli had to perform comparisons with the normal tissues of the same patient, to see if the mutation was specific to the cancer,» he said.

Two years ago, nonhuman primate studies conducted by Jason Brenchley's laboratory at the National Institute of Allergy and Infectious Diseases identified a previous unidentified cell in the gut that can produce interleuken - 17 — a cytokine that is concentrated in mucosal tissues and produced in response to bacterial and fungal antigens.

Cambridge, Mass. — June 16, 2014 — A team of researchers led by David J. Mooney, Robert P. Pinkas Family Professor of Bioengineering at the Harvard School of Engineering and Applied Sciences (SEAS), have identified a possible mechanism by which normal cells turn malignant in mammary epithelial tissues, the tissues frequently involved in breast cancer.

As for why your immune system first fails to identify the body's own cells, tissues, and / or organs as yours, in most cases the initial trigger is unknown.

The common identifying factor in most autoimmune diseases is a destructive processes called inflammation which will eventually cause the destruction of cells and tissues specific to the type of auto - immune disease he person has.

And it essentially identifies proteins that can trigger the white blood cells in your body to create histamine in soft tissues.