Sentences with phrase «identify changes in treatment»

What strategy is effective to identify changes in treatment needs that arise over the course of therapy?

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

In 1995, the state board explained its ruling by citing the Federal Election Commission's treatment of LLCs — but the FEC changed its policy in 1999, ruling that LLCs should be treated as either corporations or partnerships (depending on their self - identified tax statusIn 1995, the state board explained its ruling by citing the Federal Election Commission's treatment of LLCs — but the FEC changed its policy in 1999, ruling that LLCs should be treated as either corporations or partnerships (depending on their self - identified tax statusin 1999, ruling that LLCs should be treated as either corporations or partnerships (depending on their self - identified tax status).

«At this time, when prescription opioid use and opioid overdoses are both major threats to our public health, it is important to identify new treatment targets, such as epigenetic processes, that help to change the way that we do business in treating opioid use disorders,» said professor John Krystal, Editor of Biological Psychiatry.

The treatment group showed notable changes in the ability to identify and remember faces, which was corroborated by changes in brain patterns that arise when study participants saw a familiar face.

«This study's results can have practice changing implications on how future prostate cancer trials are designed in terms of identifying the men for these studies who are at high risk for early death due to ineffective initial treatment for their prostate cancer,» stated Anthony Victor D'Amico, MD, PhD, chief, Genitourinary Radiation Oncology, Brigham and Women's Hospital and senior author of the study.

Identifying changes in the mitochondrial DNA in PPN cholinergic neurons has the potential to allow the development of more effective treatments targeted to specific cell - types.

One study aims to identify the point during the treatment where the change in the brain occurs.

If we want to change the death rate, we need to increase the investment in understanding the biology of pancreatic cancer and identifying novel treatment strategies,» said co-author and pancreatic cancer surgeon Dr. Michael Choti, Chairman of Surgery, who holds the Hall and Mary Lucile Shannon Distinguished Chair in Surgery.

Some basic research findings are being translated into new treatments, and with the discovery of induced pluripotent stem cells in 2006, the field has seen a step - change in biological understanding that will affect the way new drugs are identified and tested and, potentially, the way cells can be generated in the lab.

Hepatic encephalopathy occurs when the liver can not remove certain toxins and chemicals, such as ammonia, from the blood.1 These toxins and chemicals then build up and enter the brain.1 Hepatic encephalopathy is one of the major complications of cirrhosis (scarring of the liver), and a leading cause of hospital re-admission due to its recurrence, despite treatment.1 It can occur suddenly in people with acute liver failure, but is seen more often in those with chronic liver disease.1 Symptoms of hepatic encephalopathy include mild confusion, forgetfulness, poor concentration and personality or mood changes, but can progress to extreme anxiety, seizures, severe confusion, jumbled and slurred speech and slow movement.1 The first step in treatment is to identify and treat any factors that cause hepatic encephalopathy.2 Once the episode has resolved, further treatment aims to reduce the production and absorption of toxins, such as ammonia.1 Generally, there are two types of medication used to reduce the likelihood of another hepatic encephalopathy episode — lactulose and rifaximin.2 However, it remains a leading cause of hospitalisations and re-hospitalisations in cirrhotic patients, despite the use of the above - mentioned standard of care treatment.

They have called attention to more or less «evenly distributed errors» across Lomborgs treatment of population, food, forests, air pollution, acid rain, climate change, and biodiversity loss, among other topics errors including all of the types I identified in his energy chapter, and more even while acknowledging, as I did, that in this potpourri Lomborg manages to get a few things right.

Additional limitations to the traditional approach include: costly failures to replicate positive results in larger trials; difficulty in determining the reasons for negative results; low yield in terms of identifying disease or intervention mechanisms due to an exclusive focus on symptom change and clinical endpoints; and, the expensive and very lengthy practice of first establishing multi-component psychosocial treatments followed by years of «unpacking» studies.

New «liquid biopsy» could help identify advanced breast cancer patients who would benefit from a change in treatment - Read More...

«By looking at changes in tumour blood vessels and the tumour stiffness and structure with ultrasound, we hope to identify the patients that are responding to the treatment, and those that aren't,» she says.

So we need to identify what changes occur early, and decide which of them are sensitive enough to use as endpoints in treatment trials.

Identifying a new «R» will take a trained eye: the changes are minimal, in the usual Germanic facelift style, and centre on an arguably more aggressive frontal design treatment and LED lighting front and rear.

Vitals monitoring to track the patients condition, support the treatment plan and immediately identify any change in medical needs

If a clean bill of health is confirmed, you may wish to consult a professional animal behaviorist to help you identify the cause of your cat's change in elimination habits and develop a treatment plan to retrain your cat to the litterbox.

Exploring Novel Treatments for IBD Researchers are looking at changes in gut bacteria that stimulate the immune system in dogs with inflammatory bowel disease to help identify novel ways to diagnose and treat this disease.

- Urine culture with susceptibility - Urine protein to creatinine ratio test - Diagnostic imaging — Using radiography (X-rays) and ultrasound to identify changes in the size, shape, and architecture of the kidneys and their plumbing may show a need for emergency treatment.

The water utility serving New York City has identified heavy precipitation events as one of its major climate - change - related concerns because such events can raise turbidity levels in some of the city's main reservoirs up to 100 times the legal limit for source quality at the utility's intake, requiring substantial additional treatment and monitoring costs (Miller and Yates, 2006).

• Reorganize the outpatient coding system and make it more efficient by streamlining information inflow • Successfully reconcile a patient data form, by quickly identifying problems in coding and changing the information before submitting it for insurance approval • Train 2 groups of hew hires in handling CPT and ICD - 9 coding as part of their induction process • Assign codes for diagnosis, procedures and treatments according to specified classification systems • Use technical coding principles to assign appropriate ICD -9-CM diagnosis • Identify chargeable items for outpatient visits and ensure that they are properly entered into the system • Perform reviews of records to assure that all component parts are present, including name, health record number and signatures

Engaged primary caregivers and other key participants in active change oriented treatment by identifying and overcoming barriers to engagement.

The Future of Family Engagement in Residential Care Settings Affronti & Levison - Johnson (2009) Residential Treatment for Children and Youth, 26 (4) View Abstract Reviews the literature on the use of family engagement practices and family - centered practices in residential programs and treatment centers in order to identify evidence - based and best practices and recommend specific strategies and critical steps needed to promote a culture and practice change initiative within residential care Treatment for Children and Youth, 26 (4) View Abstract Reviews the literature on the use of family engagement practices and family - centered practices in residential programs and treatment centers in order to identify evidence - based and best practices and recommend specific strategies and critical steps needed to promote a culture and practice change initiative within residential care treatment centers in order to identify evidence - based and best practices and recommend specific strategies and critical steps needed to promote a culture and practice change initiative within residential care settings.

Other factors for poor response to treatment identified in the literature [12, 15, 28, 31] and those observed from personal experience of delivering the programme (Unpublished) include lack of partner support, resistance to change in the home, parents» unrealistic and developmentally inappropriate expectations for children, adverse child rearing practices, and negative cognitions and perceptions of child behaviour.

As treatment progresses, a trained couples therapist navigates the process of understanding the cycles couples get stuck in and identifies what needs to change to have a more effective and positive connection.

Follow - up Assessment: Follow - up assessments occur after the initial clinical evaluation has been performed to re-evaluate the client's progress and response to treatment, current functional status, identify changes in behavior and / or condition, and ensure medical / clinical appropriateness for continued treatment.