Sentences with phrase «identify donor cells»
Historically, clinicians evaluating a patient for transplant have sought to identify donor cells that are perfectly matched to the patient's cell type, which is considered to be the optimal approach to help ensure successful outcomes and to minimize risk of graft - versus - host disease (GVHD), a serious and potentially life - threatening complication that occurs when the donated immune cells attack the patient's cells as foreign tissue.
https://www.sciencedaily.com/ Not exact matches
By dosing all the post-transplant bacteria with tetracycline and looking for blue colonies, the scientists could identify which cells had the donor DNA.
The profile of CD4 - TEMRA was highly heterogeneous across donors, with four distinct clusters identified by the single - cell analysis.
Urgent evaluation to help identify optimal hematopoietic stem cell donor for individuals with a hematologic disorder and a family history that raises concerns
We are part on the newly launched NIHR Blood and Transplant Research Unit in Donor Health and Genomics, where we coordinate theme 1 - Determinants of donation - related biomarkers.This theme will address the NIHR BTRU mandate to identify and characterise «genetic, biochemical, lifestyle and other determinants of relevant blood cell traits... and measures of iron homeostasis, including determinants of the trajectories of these factors over time among donors».
The program provides accurate, rapid genotyping and chimerism analysis; automatically identifies donor and recipient peaks in post-BMT samples, calculates percent chimerism and quality metrics for single donor or double donor cases, easily appends for longitudinal monitoring post-BMT, and has multi-lineage capabilities for chimerism analysis of T - cells, B - cells, and other cell type populations.
Moreover, there is some evidence that Graft versus Host Disease is more likely where a patient has an older donor, as their cells are more experienced in identifying foreign cells.
We developed and implemented such a nomenclature for the European human pluripotent stem cell registry (hPSCreg), which needs to: 1) unambiguously identify a registered cell line; 2) allow tracing of subclones of a particular line; and 3) enable the assignment of different lines to a specific donor origin.
We hypothesize that SSEA3 expression is either identifying another less differentiated and / or tissue specific stem cell like population that is retrieved with the donor skin biopsy or that with culture, a subpopulation of fibroblasts may acquire the ability to express SSEA3.