Sentences with phrase «identify effective drugs»
Screen novel chemical compound libraries to identify effective drugs to treat active disease.
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Draper's human organ system should be able to identify effective drugs and ineffective ones early in the drug discovery process, allowing developers to refocus resources on the strong candidates earlier and end unproductive research earlier, minimizing costs, Borenstein said.
Not exact matches
The research team currently is working to identify new biomarkers that will allow them to develop a better understanding of how drug resistance develops, and how to best design effective combinations of medications that may improve patient responses.
«Using this technology, the study is the first to discover the critical role of astroglial cells in Down syndrome as well as identify a promising pathway for exploring how a drug such as minocycline may offer an effective way to help treat it.»
The researchers also identified drugs that are effective against the cancers and could potentially be used in the fight to save the devils from extinction.
The effective drugs that the researchers identified when they compared the cancers inhibit pathways normally involved in healing, suggesting that wound repair pathways might somehow be involved in the origin of the cancers.
The antibiotic, first identified by Nosopharm, is unique and promising on two fronts: its unconventional source and its distinct way of killing bacteria, both of which suggest the compound may be effective at treating drug - resistant or hard - to - treat bacterial infections.
By 2004 Sinclair and his business colleagues had established a biotech company called Sirtris to identify drugs even more effective and long lasting than the reversatrol - sirtuin interaction.
«New study is an advance toward preventing a «post-antibiotic era»: Biologists identify drug combinations that may be highly effective at reducing growth of deadly bacteria.»
Patient - derived xenographs involve the implantation of tumor tissue into an immunodeficient mouse which becomes an avatar to help identify which drug or drug combinations are most likely to be effective for an individual cancer patient.
Her glioblastoma was too advanced, however, and she died before the desperation experiment could identify any potentially effective drugs.
Using virtual tissue technology, researchers at Indiana University have identified a potential new drug target in the fight against polycystic kidney disease, an illness with no effective FDA - approved treatment that affects 200,000 people per year in the United States.
Although effective new drugs based on such research may be decades away, near - term payoffs could include ways of identifying teens at risk of developing schizophrenia early on, or tools that help physicians better manage their patients» medications, added Steve McCarroll, director of genetics research at Broad.
«We have identified a novel therapeutic target for the treatment of severe influenza that is effective under conditions where known antiviral drugs fail to protect from death.»
In an attempt to discover more effective drug targets for influenza, scientists have recently identified several genes and molecules that are crucial for influenza virus replication.
A team of biologists from San Diego State University has developed a platform for identifying drugs that could prove to be effective against a variety of viral diseases.
«My bet is that, if the local control programme correctly identifies strains carried by each patient, and treats them with the most effective drug regimens, then the number of resistant cases will fall,» he says.
«Identifying genetic mutations associated with disease risk is an effective way to better understand disease mechanisms, identify individuals at risk, and develop novel drug targets to treat the disease,» Dr. Peter added.
«At Exeter we are already developing specific psychological therapies, running clinical trials of novel drug approaches and using - cutting edge genetic techniques to identify new targets for safe and effective therapies and to allow us to use current treatments in a more focussed way.»
They identified a particular compound, known as HPP - 4382 that has been proven effective in fighting oxidative stress and could eventually be developed into a drug.
C. Develop ways to overcome cancer's resistance to therapy Identify therapeutic targets to overcome drug resistance through studies that determine the mechanisms that lead cancer cells to become resistant to previously effective treatments.
Hear about the Science Exchange's Reproducibility Initiative, which aims to reward high - quality, reproducible research and provide a mechanism for industry to identify robust new drug targets for the development of effective new therapies.
This strategy is expected to improve early diagnoses and intervention, predict the course of a disease, identify new drug targets and select the most effective therapies for individual patients.
This requires the intervention of sophisticated robotic technology to produce the required quantities of cells on one hand, to practice drug tests under conditions to identify the compound effective to thousands of thousands of others, on the other hand.
We are committed to identifying effective new cancer therapies and researching investigational drugs.
Now, the two - year, $ 1 million PCF Challenge Award will allow Hsieh and MSK co-primary investigators Dr. Yu Chen and Dr. Brett Carver to combine their expertise to determine which drugs are effective against tumors with specific mutations and identify biomarkers that will enable oncologists to pair prostate cancer patients with the most effective treatment regimens.
deCODE's genetic research is aimed at identifying the genetic factors involved, as a means of identifying new drug and diagnostic targets that can target the underlying cause of disease and point the way towards more effective treatment and prevention strategies.
One important benefit of this genetic approach is that, even without knowing the precise genetic causes of drug resistance, researchers are able to quickly identify resistant strains — an important step towards identifying molecular markers to enable effective worldwide surveillance.
Moving forward the researchers are hoping to identify a smaller protein segment that will be just as effective, and easier to make into a drug.
Knowledge of this basic wiring diagram, and particularly of the molecules that govern the flow of information within it, helps identify drug targets that could combat the wide range of stress - related neurological diseases in a more effective and informed manner.
This approach could reveal more effective therapies and also identify drug targets that would result in fewer side effects.
The project has focussed on developing new animal models which use brain recording and behavioural tests to identify innovative and effective drugs for schizophrenia.
«Unlike other heart disease risk factors like high blood pressure or high cholesterol, we don't have specifically effective drugs to prevent heart failure, so we need to identify and verify effective strategies for prevention and emphasize these to the public,» she said.
«Unlike other heart disease risk factors like high blood pressure or high cholesterol, we don't have specifically effective drugs to prevent heart failure, so we need to identify and verify effective strategies for prevention and emphasize these to the public.»
Our universities and drug companies immediately responded to the challenge, and identified the virus and manufactured a highly effective vaccine.
A Review of Evidence - Based Approaches for Reduction of Alcohol Consumption in Native Women Who Are Pregnant or of Reproductive Age (PDF - 150 KB) Montag, Clapp, Calac, Gorman, & Chambers (2012) The American Journal of Drug and Alcohol Abuse, 38 (5) Determines the number of publications that have quantitatively evaluated interventions among American Indian and Alaskan Native women and identifies interventions that may prove useful in designing effective prevention and treatment programs.
Overall, both conditions were highly effective in improving family functioning, and OPFT was slightly more effective in reducing identified patient symptomology, including drug abuse.